Title |
The effect of mirabegron, used for overactive bladder treatment, on female sexual function: a prospective controlled study
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Published in |
BMC Urology, June 2018
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DOI | 10.1186/s12894-018-0377-9 |
Pubmed ID | |
Authors |
A. Zachariou, C. Mamoulakis, M. Filiponi, F. Dimitriadis, J. Giannakis, S. Skouros, P. Tsounapi, A. Takenaka, N. Sofikitis |
Abstract |
Αim of the study was to determine the effect of mirabegron, used for overactive bladder (OAB) treatment, on female sexual function. Eighty five sexually active women suffering from overactive bladder were prospectively enrolled in this study. Females were divided into two groups. In Group A (control), 48 patients received no treatment and in Group B, 37 patients received mirabegron 50 mg/daily for 3 months. Patients were evaluated with FSFI-Gr at the beginning of the study and again after a period of 3 months. In Group B, there was a significant increase post-treatment compared to baseline (p < 0.001) in total FSFI (20.3 (3.8) to 26.6 (4.2)) and all domains (desire: 3.0 (1.2) to 4.8 (1.2)), arousal: 3.0 (0.8) to 4.8 (0.9), lubrication: 3.9 (1.1) to 4.8 (1.2), orgasm: 3.6 (0.8) to 4.8 (1.0), satisfaction: 3.2 (0.4) to 4.0 (0.8) and pain: 3.2 (0.8) to 4.4 (1.2)). In Group A, there were no statistically significant changes in pre- and post-observation values. This study is one of the few demonstrating that management of OAB with mirabegron improves female sexual function. TRN ISRCTN17199301 , 20/10/2017, retrospectively registered. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 33% |
Italy | 1 | 11% |
Argentina | 1 | 11% |
Panama | 1 | 11% |
Belgium | 1 | 11% |
Unknown | 2 | 22% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 56% |
Practitioners (doctors, other healthcare professionals) | 2 | 22% |
Scientists | 1 | 11% |
Science communicators (journalists, bloggers, editors) | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 38 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 8 | 21% |
Researcher | 5 | 13% |
Student > Ph. D. Student | 2 | 5% |
Student > Postgraduate | 2 | 5% |
Student > Doctoral Student | 1 | 3% |
Other | 4 | 11% |
Unknown | 16 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 26% |
Nursing and Health Professions | 5 | 13% |
Social Sciences | 2 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Psychology | 1 | 3% |
Other | 3 | 8% |
Unknown | 16 | 42% |