Title |
Genetic diversity of group A rotaviruses associated with repeated outbreaks of diarrhea in a farrow-to-finish farm: identification of a porcine rotavirus strain bearing a novel VP7 genotype, G26
|
---|---|
Published in |
Veterinary Research, November 2011
|
DOI | 10.1186/1297-9716-42-112 |
Pubmed ID | |
Authors |
Ayako Miyazaki, Kazufumi Kuga, Tohru Suzuki, Mariko Kohmoto, Ken Katsuda, Hiroshi Tsunemitsu |
Abstract |
Group A rotaviruses (GARs) are one of the most common causes of diarrhea in suckling pigs. Although a number of G and P genotypes have been identified in porcine GARs, few attempts have been made to study the molecular epidemiology of these viruses associated with diarrhea outbreaks within a farm over an extended period of time. Here, we investigated the molecular characteristics of GARs that caused four outbreaks of diarrhea among suckling pigs in a farrow-to-finish farm over the course of a year. G and P genotyping of GARs detected at each outbreak demonstrated genetic diversity in this farm as follows: G9P[23] was detected at the first outbreak, G9P[13]/[22] and G9P[23] at the second, G3P[7] at the third, and G9P[23], G5P[13]/[22], and P[7] combined with an untypeable G genotype at the fourth. Sequence analysis of the detected GARs revealed that such genetic diversity could have resulted not only from the introduction of new GAR strains, but also from gene reassortment between GAR strains within the farm. Further, the GAR strain carrying the untypeable G genotype was shown to be a novel porcine GAR bearing a new G26 genotype, as confirmed by the Rotavirus Classification Working Group. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
United States | 1 | 3% |
Canada | 1 | 3% |
Unknown | 34 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 30% |
Student > Ph. D. Student | 8 | 22% |
Student > Master | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Professor > Associate Professor | 2 | 5% |
Other | 4 | 11% |
Unknown | 7 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 16 | 43% |
Veterinary Science and Veterinary Medicine | 3 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 8% |
Medicine and Dentistry | 3 | 8% |
Business, Management and Accounting | 1 | 3% |
Other | 2 | 5% |
Unknown | 9 | 24% |