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Management of adolescents with very poorly controlled type 1 diabetes by nurses: a parallel group randomized controlled trial

Overview of attention for article published in Trials, September 2015
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Title
Management of adolescents with very poorly controlled type 1 diabetes by nurses: a parallel group randomized controlled trial
Published in
Trials, September 2015
DOI 10.1186/s13063-015-0923-7
Pubmed ID
Authors

Behrouz Kassai, Muriel Rabilloud, Delphine Bernoux, Catherine Michal, Benjamin Riche, Tiphanie Ginhoux, Valérie Laudy, Daniel Terral, Catherine Didier-Wright, Veronique Maire, Catherine Dumont, Gilles Cottancin, Muriel Plasse, Guy-Patrick Jeannoel, Jamil Khoury, Claire Bony, Michel Lièvre, Jocelyne Drai, Marc Nicolino

Abstract

Fluctuation in glycemia due to hormonal changes, growth periods, physical activity, and emotions make diabetes management difficult during adolescence. Our objective was to show that a close control of patients' self-management of diabetes by nurse-counseling could probably improve metabolic control in adolescents with type 1 diabetes. We designed a multicenter, randomized controlled, parallel group, clinical trial. Seventy seven adolescents aged 12-17 years with A1C >8 % were assigned to either an intervention group (pediatrician visit every 3 months + nurse visit and phone calls) or to the control group (pediatrician visit every 3 months). The primary outcome was the evolution of the rate of A1C during the 12 months of follow-up. Secondary outcomes include patient's acceptance of the disease (evaluated by visual analog scale), the number of hypoglycemic or ketoacidosis episodes requiring hospitalization, and evaluation of A1C rate over time in each group. Seventy-seven patients were enrolled by 10 clinical centers. Seventy (89.6 %) completed the study, the evolution of A1C and participants satisfaction over the follow-up period was not significantly influenced by the nurse intervention. Nurse-led intervention to improve A1C did not show a significant benefit in adolescents with type 1 diabetes because of lack of power. Only psychological management and continuous glucose monitoring have shown, so far, a slight but significant benefit on A1C. We did not show improvements in A1C control in teenagers by nurse-led intervention. Clinical Trials.gov registration number: NCT00308256 , 28 March 2006.

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Mendeley readers

The data shown below were compiled from readership statistics for 223 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Italy 1 <1%
Unknown 221 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 37 17%
Student > Bachelor 35 16%
Researcher 19 9%
Student > Doctoral Student 17 8%
Student > Ph. D. Student 16 7%
Other 32 14%
Unknown 67 30%
Readers by discipline Count As %
Medicine and Dentistry 51 23%
Nursing and Health Professions 44 20%
Psychology 20 9%
Sports and Recreations 9 4%
Social Sciences 7 3%
Other 16 7%
Unknown 76 34%