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Immunogenicity of panitumumab in combination chemotherapy clinical trials

Overview of attention for article published in BMC Clinical Pharmacology, November 2011
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Title
Immunogenicity of panitumumab in combination chemotherapy clinical trials
Published in
BMC Clinical Pharmacology, November 2011
DOI 10.1186/1472-6904-11-17
Pubmed ID
Authors

Dohan Weeraratne, Alin Chen, Jason J Pennucci, Chi-Yuan Wu, Kathy Zhang, Jacqueline Wright, Juan José Pérez-Ruixo, Bing-Bing Yang, Arunan Kaliyaperumal, Shalini Gupta, Steven J Swanson, Narendra Chirmule, Marta Starcevic

Abstract

Panitumumab is a fully human antibody against the epidermal growth factor receptor that is indicated for the treatment of metastatic colorectal cancer (mCRC) after disease progression on standard chemotherapy. The purpose of this analysis was to examine the immunogenicity of panitumumab and to evaluate the effect of anti-panitumumab antibodies on pharmacokinetic and safety profiles in patients with mCRC receiving panitumumab in combination with oxaliplatin- or irinotecan-based chemotherapies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 2%
Unknown 47 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 27%
Student > Bachelor 5 10%
Student > Master 5 10%
Other 3 6%
Student > Ph. D. Student 3 6%
Other 6 13%
Unknown 13 27%
Readers by discipline Count As %
Medicine and Dentistry 14 29%
Agricultural and Biological Sciences 7 15%
Immunology and Microbiology 3 6%
Biochemistry, Genetics and Molecular Biology 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 13%
Unknown 13 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2011.
All research outputs
#14,721,336
of 22,656,971 outputs
Outputs from BMC Clinical Pharmacology
#45
of 56 outputs
Outputs of similar age
#94,559
of 142,895 outputs
Outputs of similar age from BMC Clinical Pharmacology
#6
of 7 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 56 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 142,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.