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Small doses of epinephrine prolong the recovery from a rocuronium-induced neuromuscular block: a case report

Overview of attention for article published in BMC Anesthesiology, July 2018
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Title
Small doses of epinephrine prolong the recovery from a rocuronium-induced neuromuscular block: a case report
Published in
BMC Anesthesiology, July 2018
DOI 10.1186/s12871-018-0544-2
Pubmed ID
Authors

Hubert J. Schmitt

Abstract

During anaesthesia it is not uncommon to administer epinephrine in patients blocked by non-depolarizing muscle relaxants. However, there are few reports on possible interaction of epinephrine with neuromuscular transmission in humans. An otherwise healthy 74-yr-old man underwent transurethral resection of a benign prostatic hyperplasia under total intravenous anaesthesia. Because of repeated drop in heart rate and blood pressure the patient received in total three bolus of epinephrine 5 μg, respectively. Each time this small dose of epinephrine intensified a rocuronium-induced neuromuscular block verified by acceleromygraphy. Further anaesthetic course was uneventful. In this case reported here small doses of intravenously administered epinephrine markedly prolonged a rocuronium-induced neuromuscular block. Given the widely used co-administration of epinephrine and muscle relaxants possible adrenergic interference with neuromuscular transmission would have implications for daily anaesthetic practice.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 18%
Researcher 2 18%
Lecturer 1 9%
Student > Ph. D. Student 1 9%
Student > Bachelor 1 9%
Other 0 0%
Unknown 4 36%
Readers by discipline Count As %
Medicine and Dentistry 4 36%
Pharmacology, Toxicology and Pharmaceutical Science 2 18%
Computer Science 1 9%
Nursing and Health Professions 1 9%
Unknown 3 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2018.
All research outputs
#20,527,576
of 23,096,849 outputs
Outputs from BMC Anesthesiology
#1,196
of 1,516 outputs
Outputs of similar age
#286,266
of 326,767 outputs
Outputs of similar age from BMC Anesthesiology
#45
of 55 outputs
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So far Altmetric has tracked 1,516 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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