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The impact of repetitive navigated transcranial magnetic stimulation coil positioning and stimulation parameters on human language function

Overview of attention for article published in European Journal of Medical Research, April 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Title
The impact of repetitive navigated transcranial magnetic stimulation coil positioning and stimulation parameters on human language function
Published in
European Journal of Medical Research, April 2015
DOI 10.1186/s40001-015-0138-0
Pubmed ID
Authors

Nico Sollmann, Sebastian Ille, Thomas Obermueller, Chiara Negwer, Florian Ringel, Bernhard Meyer, Sandro M Krieg

Abstract

Repetitive navigated transcranial magnetic stimulation (rTMS) in combination with object naming is able to elicit naming errors by stimulating language-related brain regions. However, stimulation results mainly depend on coil positioning and stimulation parameters, which have not been investigated since the implementation of neuronavigation to transcranial magnetic stimulation. Therefore, the following three parameters were systematically examined in the present study: coil angulation, stimulation frequency, and stimulation intensity. Five healthy, right-handed subjects underwent rTMS language mapping of Broca's as well as Wernicke's areas of the left hemisphere. During mapping sessions, coil angulation was changed clockwise in 45° steps, and the stimulation frequency and intensity were varied within a considerably wide range. For angulation, the anterior-posterior (ap) coil orientation was used as reference position. An angulation of 90° to ap coil orientation led to the highest rate of naming errors within Broca's area, whereas an inhomogeneous distribution of angulations was observed during stimulation of Wernicke's area. Therefore, ap coil orientation, which is regarded as standard in rTMS language mapping, could not be approved as the optimal position. With regard to stimulation parameters, 20 Hz and 120% of the resting motor threshold (RMT) were defined as optimal. Coil angulation, stimulation frequency, and stimulation intensity have significant impacts on language impairment during rTMS mapping. The variation of only one of these parameters already leads to a clearer disruption of language performance. Therefore, individually adapted stimulation protocols have to be determined prior to language mapping in order to improve mapping results.

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The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 23%
Student > Master 10 19%
Student > Doctoral Student 4 8%
Student > Ph. D. Student 4 8%
Professor 3 6%
Other 7 13%
Unknown 12 23%
Readers by discipline Count As %
Neuroscience 10 19%
Psychology 9 17%
Medicine and Dentistry 5 10%
Computer Science 4 8%
Engineering 3 6%
Other 3 6%
Unknown 18 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2015.
All research outputs
#5,447,195
of 25,374,917 outputs
Outputs from European Journal of Medical Research
#165
of 923 outputs
Outputs of similar age
#64,268
of 279,166 outputs
Outputs of similar age from European Journal of Medical Research
#7
of 21 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 923 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,166 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.