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Lipid profiles in adolescents with and without asthma: Korea National Health and nutrition examination survey data

Overview of attention for article published in Lipids in Health and Disease, July 2018
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Title
Lipid profiles in adolescents with and without asthma: Korea National Health and nutrition examination survey data
Published in
Lipids in Health and Disease, July 2018
DOI 10.1186/s12944-018-0807-4
Pubmed ID
Authors

Sun-Hye Ko, Jaewook Jeong, Myong Ki Baeg, Kyung-Do Han, Hwan Soo Kim, Jong-seo Yoon, Hyun Hee Kim, Jin Tack Kim, Yoon Hong Chun

Abstract

Metabolic syndrome and dyslipidemia contribute to the development of a pro-inflammatory state in asthma. However, studies investigating the association between asthma and dyslipidemia have reported conflicting results. This study aimed to uncover the relationship between asthma and lipid profiles in adolescents using a national health and nutrition survey. This cross-sectional study analyzed the 2010-2012 Korea National Health and Nutrition Examination Survey data and included 2841 subjects aged 11-18 years with fasting blood sample data. Serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels were analyzed. We compared asthma prevalence between high-risk and low-risk lipid groups. There were 123 adolescents with asthma and 2718 without asthma (controls). The TC/HDL-C ratio, LDL-C/HDL-C ratio, and non-HDL-C levels were significantly higher in the asthma group than in the non-asthma group (P < 0.05). The high-risk groups displayed significantly higher asthma prevalence with higher TC, TG, LDL-C, and non-HDL-C levels and TG/HDL-C ratio than the low-risk groups (P < 0.05). After adjusting for potential confounding factors, the high-risk groups were associated with asthma according to their higher TC levels (adjusted odds ratio, 1.69; 95% confidence interval, 1.012-2.822) and TG/HDL-C ratios (adjusted odds ratio, 1.665; 95% confidence interval, 1.006-2.756). Asthma prevalence was greater in adolescents with a high TC level and TG/HDL-C ratio. In addition to the standard lipid profile, elevated TG/HDL-C ratio can be used as a useful additional lipid measure to evaluate interactions between dyslipidemia and asthma.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 19%
Student > Postgraduate 4 11%
Other 3 8%
Student > Ph. D. Student 3 8%
Student > Master 3 8%
Other 6 16%
Unknown 11 30%
Readers by discipline Count As %
Medicine and Dentistry 10 27%
Nursing and Health Professions 6 16%
Biochemistry, Genetics and Molecular Biology 2 5%
Veterinary Science and Veterinary Medicine 2 5%
Agricultural and Biological Sciences 2 5%
Other 4 11%
Unknown 11 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2018.
All research outputs
#20,527,576
of 23,096,849 outputs
Outputs from Lipids in Health and Disease
#1,210
of 1,459 outputs
Outputs of similar age
#287,707
of 329,174 outputs
Outputs of similar age from Lipids in Health and Disease
#32
of 39 outputs
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