Title |
Allergen immunotherapy on the way to product-based evaluation—a WAO statement
|
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Published in |
World Allergy Organization Journal, September 2015
|
DOI | 10.1186/s40413-015-0078-8 |
Pubmed ID | |
Authors |
Claus Bachert, Mark Larché, Sergio Bonini, Giorgio Walter Canonica, Thomas Kündig, Desiree Larenas-Linnemann, Dennis Ledford, Hugo Neffen, Ruby Pawankar, Giovanni Passalacqua |
Abstract |
Allergen immunotherapy (AIT) is widely used in clinical practice for patients with moderate to severe allergic rhinitis due to inhalant allergens and may be delivered via subcutaneous (SCIT) and sublingual routes (SLIT). However, the quality of evidence for individual AIT products is very heterogeneous, and extensions of overall conclusions ("class effects") on the efficacy and disease-modifying effects to all AIT products are unjustified. In contrast, each product needs to be evaluated individually, based on available study results, to justify efficacy and specific claims on sustained and disease modifying effects per allergen and targeted patient group (children vs. adults, allergic rhinitis vs. asthma). WAO intends to support the current development to evidence-based AIT, which ultimately will lead to a more efficacious treatment of allergic patients and the appropriate recognition of AIT. |
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Geographical breakdown
Country | Count | As % |
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Ecuador | 1 | 13% |
Argentina | 1 | 13% |
Unknown | 6 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 88% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 18% |
Student > Ph. D. Student | 5 | 13% |
Professor | 4 | 10% |
Student > Doctoral Student | 3 | 8% |
Student > Master | 3 | 8% |
Other | 9 | 23% |
Unknown | 9 | 23% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 35% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 13% |
Nursing and Health Professions | 2 | 5% |
Immunology and Microbiology | 2 | 5% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 3 | 8% |
Unknown | 13 | 33% |