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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Impact of statin therapy on coronary plaque composition: a systematic review and meta-analysis of virtual histology intravascular ultrasound studies
|
|---|---|
| Published in |
BMC Medicine, September 2015
|
| DOI | 10.1186/s12916-015-0459-4 |
| Pubmed ID | |
| Authors |
Maciej Banach, Corina Serban, Amirhossein Sahebkar, Dimitri P. Mikhailidis, Sorin Ursoniu, Kausik K. Ray, Jacek Rysz, Peter P. Toth, Paul Muntner, Svetlana Mosteoru, Hector M. García-García, G. Kees Hovingh, John JP Kastelein, Patrick W. Serruys, Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group |
| Abstract |
Virtual histology intravascular ultrasound (VH-IVUS) imaging is an innovative tool for the morphological evaluation of coronary atherosclerosis. Evidence for the effects of statin therapy on VH-IVUS parameters have been inconclusive. Consequently, we performed a systematic review and meta-analysis to investigate the impact of statin therapy on plaque volume and its composition using VH-IVUS. The search included PubMed, Cochrane Library, Scopus and Embase (through 30 November 2014) to identify prospective studies investigating the effects of statin therapy on plaque volume and its composition using VH-IVUS. We identified nine studies with 16 statin treatment arms and 830 participants. There was a significant effect of statin therapy in reducing plaque volume (standardized mean difference (SMD): -0.137, 95 % confidence interval (CI): -0.255, -0.019; P = 0.023), external elastic membrane volume (SMD: -0.097, 95 % CI: -0.183, -0.011; P = 0.027) but not lumen volume (SMD: -0.025, 95 % CI: -0.110, +0.061; P = 0.574). There was a significant reduction in fibrous plaque volume (SMD: -0.129, 95 % CI: -0.255, -0.003; P = 0.045) and an increase of dense calcium volume (SMD: +0.229, 95 % CI: +0.008, +0.450; P = 0.043), while changes in fibro-fatty (SMD: -0.247, 95 % CI: -0.592, +0.098; P = 0.16) and necrotic core (SMD: +0.011, 95 % CI: -0.144, +0.165; P = 0.892) tissue volumes were not statistically significant. This meta-analysis indicates a significant effect of statin therapy on plaque and external elastic membrane volumes and fibrous and dense calcium volumes. There was no effect on lumen volume, fibro-fatty and necrotic tissue volumes. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 13% |
| Cyprus | 1 | 6% |
| United States | 1 | 6% |
| Canada | 1 | 6% |
| Netherlands | 1 | 6% |
| Israel | 1 | 6% |
| Poland | 1 | 6% |
| Unknown | 8 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 63% |
| Practitioners (doctors, other healthcare professionals) | 3 | 19% |
| Scientists | 3 | 19% |
Mendeley readers
The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 131 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 24 | 18% |
| Other | 16 | 12% |
| Student > Ph. D. Student | 15 | 11% |
| Researcher | 14 | 11% |
| Professor > Associate Professor | 12 | 9% |
| Other | 25 | 19% |
| Unknown | 27 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 59 | 44% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
| Agricultural and Biological Sciences | 4 | 3% |
| Engineering | 4 | 3% |
| Other | 16 | 12% |
| Unknown | 37 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2023.
All research outputs
#1,711,366
of 25,523,622 outputs
Outputs from BMC Medicine
#1,211
of 4,042 outputs
Outputs of similar age
#23,115
of 284,730 outputs
Outputs of similar age from BMC Medicine
#45
of 100 outputs
Altmetric has tracked 25,523,622 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,042 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.7. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,730 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 100 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.