↓ Skip to main content

Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety

Overview of attention for article published in Journal of Translational Medicine, May 2011
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
49 Dimensions

Readers on

mendeley
56 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety
Published in
Journal of Translational Medicine, May 2011
DOI 10.1186/1479-5876-9-55
Pubmed ID
Authors

Akio Ido, Akihiro Moriuchi, Masatsugu Numata, Toshinori Murayama, Satoshi Teramukai, Hiroyuki Marusawa, Naohisa Yamaji, Hitoshi Setoyama, Il-Deok Kim, Tsutomu Chiba, Shuji Higuchi, Masayuki Yokode, Masanori Fukushima, Akira Shimizu, Hirohito Tsubouchi

Abstract

Hepatocyte growth factor (HGF) stimulates hepatocyte proliferation, and also acts as an anti-apoptotic factor. Therefore, HGF is a potential therapeutic agent for treatment of fatal liver diseases. We performed a translational medicine protocol with recombinant human HGF (rh-HGF), including a phase I/II study of patients with fulminant hepatitis (FH) or late-onset hepatic failure (LOHF), in order to examine the safety, pharmacokinetics, and clinical efficacy of this molecule.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Russia 1 2%
Unknown 54 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 32%
Student > Master 7 13%
Student > Ph. D. Student 7 13%
Other 4 7%
Student > Doctoral Student 3 5%
Other 6 11%
Unknown 11 20%
Readers by discipline Count As %
Medicine and Dentistry 21 38%
Agricultural and Biological Sciences 7 13%
Biochemistry, Genetics and Molecular Biology 6 11%
Nursing and Health Professions 2 4%
Immunology and Microbiology 2 4%
Other 7 13%
Unknown 11 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2011.
All research outputs
#15,238,442
of 22,656,971 outputs
Outputs from Journal of Translational Medicine
#2,209
of 3,950 outputs
Outputs of similar age
#83,724
of 109,939 outputs
Outputs of similar age from Journal of Translational Medicine
#24
of 26 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,950 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,939 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.