Title |
Serum lipophilic antioxidants levels are associated with leucocyte telomere length among US adults
|
---|---|
Published in |
Lipids in Health and Disease, July 2018
|
DOI | 10.1186/s12944-018-0781-x |
Pubmed ID | |
Authors |
Mohsen Mazidi, Andre Pascal Kengne, L. J. Cheskin, Maciej Banach |
Abstract |
To examine the association between serum concentrations of antioxidant and telomere length (TL) in U.S adults. Participants of the National Health and Nutrition Examination Survey (NHANES) with data available on TL measures from 2001 to 2002 were included. Serum lipophilic antioxidants level was measured using high performance liquid chromatography with photodiode array detection. We used analysis of co-variance and multivariable-adjusted linear regression models, accounting for the survey design and sample weights. Of the 5992 eligible participants, 47.5% (n = 2844) were men. The mean age was 46.9 years overall, 47.2 years in men and 46.6 in women (p = 0.071). In age, sex, race, education, marital status, adiposity, smoking, C-reactive protein adjusted linear regressions, antioxidant, serum α-carotene, trans-β-carotene, cis- β-carotene, β-cryptoxanthin and combined Lutein/zeaxanthin were positively and significantly associated with TL (all p < 0.001). Our findings support a possible positive association between serum concentrations of lipophylic antioxidant and TL. The implications of this association deserve further investigation. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Poland | 3 | 25% |
United Kingdom | 2 | 17% |
Mexico | 1 | 8% |
Unknown | 6 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 58% |
Practitioners (doctors, other healthcare professionals) | 4 | 33% |
Scientists | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 32 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 9 | 28% |
Researcher | 3 | 9% |
Student > Master | 3 | 9% |
Lecturer | 2 | 6% |
Professor | 2 | 6% |
Other | 5 | 16% |
Unknown | 8 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 19% |
Biochemistry, Genetics and Molecular Biology | 5 | 16% |
Medicine and Dentistry | 5 | 16% |
Nursing and Health Professions | 3 | 9% |
Chemical Engineering | 1 | 3% |
Other | 3 | 9% |
Unknown | 9 | 28% |