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The largest reported papillary thyroid carcinoma arising in struma ovarii and metastasis to opposite ovary: case report and review of literature

Overview of attention for article published in Thyroid Research, July 2018
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Title
The largest reported papillary thyroid carcinoma arising in struma ovarii and metastasis to opposite ovary: case report and review of literature
Published in
Thyroid Research, July 2018
DOI 10.1186/s13044-018-0054-9
Pubmed ID
Authors

Mohamed S. Al Hassan, Tamer Saafan, Walid El Ansari, Afaf A. Al Ansari, Mahmoud A. Zirie, Hanan Farghaly, Abdelrahman Abdelaal

Abstract

Malignant struma ovarii (MSO) is a very rare, germ cell tumor of the ovary, histologically identical to differentiated thyroid cancers. Struma ovarii (SO) is difficult to diagnose on clinical basis or imaging and is mostly discovered incidentally, with few published cases in the literature. A 42-year old primiparous woman presented with abdominal pain and midline pelvic palpable firm mass arising from the pelvis. Imaging showed pelvic solid cystic mass. Total abdominal hysterectomy, bilateral salpingo-oopherectomy (TAH BSO) and infracolic omentectomy were performed. Histopathology revealed left ovary papillary thyroid carcinoma (PTC) arising in SO (11 cm) and metastatic papillary thyroid carcinoma in the right ovary. Thyroid functions tests were all normal, ultrasound thyroid showed two complex nodules in the left thyroid lobe. Total thyroidectomy was decided, but the patient refused further surgical management and was lost to follow up as she left the country. We undertook a comprehensive literature search, and MSO and thyroid management data from 23 additional publications were analyzed and tabulated. This PTC MSO is probably the largest reported in the literature. Among the different surgeries for MSO, TAH + BSO appears to have the best clinical outcome. However, unilateral salpingo-oopherectomy/ unilateral oophorectomy and bilateral salpingo-oopherectomy also seem effective. Ovarian cystectomy alone seems associated with higher recurrence. There remains no consensus on the associations between MSO tumor size and potential extent of metastasis, and about the management of thyroid gland. However, surveillance and thyroid gland work up to detect concurrent thyroid cancer are recommended.

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Mendeley readers

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The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 19%
Researcher 3 9%
Student > Doctoral Student 2 6%
Other 1 3%
Lecturer 1 3%
Other 2 6%
Unknown 17 53%
Readers by discipline Count As %
Medicine and Dentistry 10 31%
Biochemistry, Genetics and Molecular Biology 3 9%
Business, Management and Accounting 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Energy 1 3%
Other 1 3%
Unknown 15 47%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2018.
All research outputs
#20,527,576
of 23,096,849 outputs
Outputs from Thyroid Research
#157
of 195 outputs
Outputs of similar age
#288,196
of 329,806 outputs
Outputs of similar age from Thyroid Research
#4
of 4 outputs
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So far Altmetric has tracked 195 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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