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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate
|
|---|---|
| Published in |
Journal of Biomedical Science, July 2018
|
| DOI | 10.1186/s12929-018-0462-0 |
| Pubmed ID | |
| Authors |
Hong-Ru Chen, Yen-Chung Lai, Trai-Ming Yeh |
| Abstract |
Dengue virus (DENV) infection is the most common mosquito-transmitted viral infection. DENV infection can cause mild dengue fever or severe dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). Hemorrhage and vascular leakage are two characteristic symptoms of DHF/DSS. However, due to the limited understanding of dengue pathogenesis, no satisfactory therapies to treat nor vaccine to prevent dengue infection are available, and the mortality of DHF/DSS is still high. DENV nonstructural protein 1 (NS1), which can be secreted in patients' sera, has been used as an early diagnostic marker for dengue infection for many years. However, the roles of NS1 in dengue-induced vascular leakage were described only recently. In this article, the pathogenic roles of DENV NS1 in hemorrhage and vascular leakage are reviewed, and the possibility of using NS1 as a therapeutic target and vaccine candidate is discussed. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 438 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 438 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 63 | 14% |
| Student > Master | 56 | 13% |
| Student > Ph. D. Student | 41 | 9% |
| Researcher | 28 | 6% |
| Student > Doctoral Student | 11 | 3% |
| Other | 35 | 8% |
| Unknown | 204 | 47% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 75 | 17% |
| Medicine and Dentistry | 45 | 10% |
| Immunology and Microbiology | 32 | 7% |
| Agricultural and Biological Sciences | 23 | 5% |
| Engineering | 12 | 3% |
| Other | 37 | 8% |
| Unknown | 214 | 49% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2021.
All research outputs
#6,878,604
of 25,385,509 outputs
Outputs from Journal of Biomedical Science
#283
of 1,101 outputs
Outputs of similar age
#109,336
of 340,712 outputs
Outputs of similar age from Journal of Biomedical Science
#4
of 13 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,712 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.