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Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report

Overview of attention for article published in International Archives of Medicine, November 2010
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 102)
  • High Attention Score compared to outputs of the same age (99th percentile)

Mentioned by

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20 news outlets
twitter
26 X users
facebook
1 Facebook page

Citations

dimensions_citation
75 Dimensions

Readers on

mendeley
92 Mendeley
connotea
1 Connotea
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Title
Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report
Published in
International Archives of Medicine, November 2010
DOI 10.1186/1755-7682-3-30
Pubmed ID
Authors

Thomas E Ichim, Fabio Solano, Fabian Lara, Eugenia Paris, Federico Ugalde, Jorge Paz Rodriguez, Boris Minev, Vladimir Bogin, Famela Ramos, Erik J Woods, Michael P Murphy, Amit N Patel, Robert J Harman, Neil H Riordan

Abstract

Cellular therapy for spinal cord injury (SCI) is overviewed focusing on bone marrow mononuclear cells, olfactory ensheathing cells, and mesenchymal stem cells. A case is made for the possibility of combining cell types, as well as for allogeneic use. We report the case of 29 year old male who suffered a crush fracture of the L1 vertebral body, lacking lower sensorimotor function, being a score A on the ASIA scale. Stem cell therapy comprised of intrathecal administration of allogeneic umbilical cord blood ex-vivo expanded CD34 and umbilical cord matrix MSC was performed 5 months, 8 months, and 14 months after injury. Cell administration was well tolerated with no adverse effects observed. Neuropathic pain subsided from intermittent 10/10 to once a week 3/10 VAS. Recovery of muscle, bowel and sexual function was noted, along with a decrease in ASIA score to "D". This case supports further investigation into allogeneic-based stem cell therapies for SCI.

X Demographics

X Demographics

The data shown below were collected from the profiles of 26 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Austria 1 1%
South Africa 1 1%
Taiwan 1 1%
United States 1 1%
Unknown 87 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 27%
Researcher 12 13%
Student > Bachelor 11 12%
Student > Master 8 9%
Professor 7 8%
Other 18 20%
Unknown 11 12%
Readers by discipline Count As %
Medicine and Dentistry 24 26%
Agricultural and Biological Sciences 20 22%
Biochemistry, Genetics and Molecular Biology 9 10%
Neuroscience 7 8%
Engineering 5 5%
Other 8 9%
Unknown 19 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 167. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2024.
All research outputs
#248,838
of 25,770,491 outputs
Outputs from International Archives of Medicine
#2
of 102 outputs
Outputs of similar age
#631
of 111,660 outputs
Outputs of similar age from International Archives of Medicine
#2
of 4 outputs
Altmetric has tracked 25,770,491 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 102 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,660 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.