You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Enhancer-driven chromatin interactions during development promote escape from silencing by a long non-coding RNA
|
|---|---|
| Published in |
Epigenetics & Chromatin, November 2011
|
| DOI | 10.1186/1756-8935-4-21 |
| Pubmed ID | |
| Authors |
Lisa Korostowski, Anjali Raval, Gillian Breuer, Nora Engel |
| Abstract |
Gene regulation in eukaryotes is a complex process entailing the establishment of transcriptionally silent chromatin domains interspersed with regions of active transcription. Imprinted domains consist of clusters of genes, some of which exhibit parent-of-origin dependent monoallelic expression, while others are biallelic. The Kcnq1 imprinted domain illustrates the complexities of long-range regulation that coexists with local exceptions. A paternally expressed repressive non-coding RNA, Kcnq1ot1, regulates a domain of up to 750 kb, encompassing 14 genes. We study how the Kcnq1 gene, initially silenced by Kcnq1ot1, undergoes tissue-specific escape from imprinting during development. Specifically, we uncover the role of chromosome conformation during these events. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 5% |
| Italy | 2 | 3% |
| Portugal | 1 | 2% |
| Canada | 1 | 2% |
| Denmark | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 55 | 86% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 31% |
| Student > Ph. D. Student | 13 | 20% |
| Student > Master | 9 | 14% |
| Student > Bachelor | 5 | 8% |
| Professor > Associate Professor | 3 | 5% |
| Other | 8 | 13% |
| Unknown | 6 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 66% |
| Biochemistry, Genetics and Molecular Biology | 14 | 22% |
| Unspecified | 1 | 2% |
| Social Sciences | 1 | 2% |
| Medicine and Dentistry | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 5 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2023.
All research outputs
#7,004,379
of 24,387,992 outputs
Outputs from Epigenetics & Chromatin
#270
of 593 outputs
Outputs of similar age
#40,840
of 144,783 outputs
Outputs of similar age from Epigenetics & Chromatin
#1
of 4 outputs
Altmetric has tracked 24,387,992 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 593 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 144,783 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them