Title |
Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment
|
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Published in |
BMC Cancer, November 2011
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DOI | 10.1186/1471-2407-11-486 |
Pubmed ID | |
Authors |
Peter A Fasching, Katharina Heusinger, Lothar Haeberle, Melitta Niklos, Alexander Hein, Christian M Bayer, Claudia Rauh, Ruediger Schulz-Wendtland, Mayada R Bani, Michael Schrauder, Laura Kahmann, Michael P Lux, Johanna D Strehl, Arndt Hartmann, Arno Dimmler, Matthias W Beckmann, David L Wachter |
Abstract |
The pathological complete response (pCR) after neoadjuvant chemotherapy is a surrogate marker for a favorable prognosis in breast cancer patients. Factors capable of predicting a pCR, such as the proliferation marker Ki67, may therefore help improve our understanding of the drug response and its effect on the prognosis. This study investigated the predictive and prognostic value of Ki67 in patients with invasive breast cancer receiving neoadjuvant treatment for breast cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 25% |
United States | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 1% |
Germany | 1 | <1% |
Unknown | 170 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 25 | 14% |
Student > Master | 21 | 12% |
Student > Bachelor | 20 | 12% |
Student > Ph. D. Student | 19 | 11% |
Student > Doctoral Student | 9 | 5% |
Other | 33 | 19% |
Unknown | 46 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 62 | 36% |
Agricultural and Biological Sciences | 27 | 16% |
Biochemistry, Genetics and Molecular Biology | 14 | 8% |
Unspecified | 4 | 2% |
Nursing and Health Professions | 3 | 2% |
Other | 13 | 8% |
Unknown | 50 | 29% |