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Mendeley readers
| Title |
NF-κB/STAT3/PI3K signaling crosstalk in iMycEμ B lymphoma
|
|---|---|
| Published in |
Molecular Cancer, April 2010
|
| DOI | 10.1186/1476-4598-9-97 |
| Pubmed ID | |
| Authors |
Seong-Su Han, Hwakyung Yun, Dong-Ju Son, Van S. Tompkins, Liangping Peng, Seung-Tae Chung, Joong-Su Kim, Eun-Sung Park, Siegfried Janz |
| Abstract |
Myc is a well known driver of lymphomagenesis, and Myc-activating chromosomal translocation is the recognized hallmark of Burkitt lymphoma, an aggressive form of non-Hodgkin's lymphoma. We developed a model that mimics this translocation event by inserting a mouse Myc cDNA gene into the immunoglobulin heavy chain locus, just upstream of the intronic Emu enhancer. These mice, designated iMyc E mu, readily develop B-cell lymphoma. To study the mechanism of Myc-induced lymphoma, we analyzed signaling pathways in lymphoblastic B-cell lymphomas (LBLs) from iMyc E mu mice, and an LBL-derived cell line, iMyc E mu-1. |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Ukraine | 1 | 2% |
| Germany | 1 | 2% |
| France | 1 | 2% |
| Unknown | 57 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 31% |
| Student > Ph. D. Student | 19 | 31% |
| Student > Master | 6 | 10% |
| Student > Postgraduate | 4 | 7% |
| Other | 4 | 7% |
| Other | 7 | 11% |
| Unknown | 2 | 3% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 48% |
| Biochemistry, Genetics and Molecular Biology | 14 | 23% |
| Medicine and Dentistry | 7 | 11% |
| Immunology and Microbiology | 2 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 2 | 3% |
| Unknown | 6 | 10% |