Title |
Infection of novel reassortant H1N2 and H3N2 swine influenza A viruses in the guinea pig model
|
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Published in |
Veterinary Research, July 2018
|
DOI | 10.1186/s13567-018-0572-4 |
Pubmed ID | |
Authors |
Rodrigo Tapia, Victoria García, Juan Mena, Sergio Bucarey, Rafael A. Medina, Víctor Neira |
Abstract |
Novel H1N2 and H3N2 swine influenza A viruses (IAVs) were identified in commercial farms in Chile. These viruses contained H1, H3 and N2 sequences, genetically divergent from IAVs described worldwide, associated with pandemic internal genes. Guinea pigs were used as human surrogate to evaluate the infection dynamics of these reassortant viruses, compared with a pandemic H1N1 virus. All viruses replicated and were shed in the upper respiratory tract without prior adaptation although H1N2 viruses showed the highest shedding titers. This could have public health importance, emphasizing the need to carry out further studies to evaluate the zoonotic potential of these viruses. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 24% |
Student > Bachelor | 3 | 12% |
Other | 2 | 8% |
Student > Master | 2 | 8% |
Librarian | 2 | 8% |
Other | 5 | 20% |
Unknown | 5 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 9 | 36% |
Nursing and Health Professions | 2 | 8% |
Agricultural and Biological Sciences | 2 | 8% |
Immunology and Microbiology | 1 | 4% |
Economics, Econometrics and Finance | 1 | 4% |
Other | 2 | 8% |
Unknown | 8 | 32% |