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Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain

Overview of attention for article published in Veterinary Research, September 2015
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Title
Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain
Published in
Veterinary Research, September 2015
DOI 10.1186/s13567-015-0249-1
Pubmed ID
Authors

Xinsheng Liu, Chun-Ming Lin, Thavamathi Annamalai, Xiang Gao, Zhongyan Lu, Malak A Esseili, Kwonil Jung, Mohamed El-Tholoth, Linda J Saif, Qiuhong Wang

Abstract

The infectious dose of a virus pool of original US PEDV strain PC22A was determined in 4-day-old, cesarean-derived, colostrum-deprived (CDCD) piglets. The median pig diarrhea dose (PDD50) of the virus pool was determined as 7.35 log10 PDD50/mL, similar to the cell culture infectious titer, 7.75 log10 plaque-forming units (PFU)/mL. 100 PDD50 caused watery diarrhea in all conventional suckling piglets (n = 12) derived from a PEDV-naive sow, whereas 1000 and 10 000 PDD50 did not cause diarrhea in piglets derived from two PEDV-field exposed-recovered sows. This information is important for future PEDV challenge studies and validation of PEDV vaccines.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 23%
Researcher 10 19%
Other 6 12%
Student > Doctoral Student 5 10%
Student > Bachelor 4 8%
Other 6 12%
Unknown 9 17%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 10 19%
Medicine and Dentistry 8 15%
Agricultural and Biological Sciences 8 15%
Biochemistry, Genetics and Molecular Biology 4 8%
Nursing and Health Professions 2 4%
Other 7 13%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2015.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from Veterinary Research
#1,035
of 1,337 outputs
Outputs of similar age
#209,726
of 286,220 outputs
Outputs of similar age from Veterinary Research
#29
of 38 outputs
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