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Incidence and serotype distribution of invasive group B streptococcal disease in young infants: a multi-country observational study

Overview of attention for article published in BMC Pediatrics, October 2015
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Title
Incidence and serotype distribution of invasive group B streptococcal disease in young infants: a multi-country observational study
Published in
BMC Pediatrics, October 2015
DOI 10.1186/s12887-015-0460-2
Pubmed ID
Authors

Luis Rivera, Xavier Sáez-Llorens, Jesus Feris-Iglesias, Margaret Ip, Samir Saha, Peter V. Adrian, Shabir A. Madhi, Irving C. Boudville, Marianne C. Cunnington, Javier M. Casellas, Karen S. Slobod

Abstract

Group B Streptococcus (GBS) is a leading cause of serious infection in very young infants. Robust incidence data from many geographic regions, including Latin America and Asia, are however lacking. A multicenter, hospital-based observational study was performed in Panama, Dominican Republic, Hong Kong and Bangladesh. All represented urban, tertiary referral hospitals, except Bangladesh. GBS cases (microbiological isolation from normally sterile sites in infants aged 0-89 days) were collected over 12 months. At 2.35 (95 % CI: 1.74-3.18) cases per 1000 live births, the incidence of early onset GBS disease (EOD) was highest in the Dominican Republic, compared with 0.76 (95 % CI: 0.41-1.39) in Hong Kong and 0.77 (95 % CI: 0.44-1.35) in Panama, while no cases were identified in Bangladesh. Over 90 % of EOD cases occurred on the first day of life, with case fatality ratios ranging from 6.7 % to 40 %, varying by center, age of onset and clinical presentation. Overall, 90 % of GBS (EOD and late onset disease) was due to serotypes Ia, Ib and III. The incidence rate of early onset GBS infection reported in Dominican Republic was not dissimilar from that described in the United States prior to screening and intrapartum antibiotic prophylaxis, while the incidence in Hong Kong was higher than previously reported in the Asian region. The failure to identify GBS cases in Bangladesh highlights a need to better understand the contribution of population, healthcare and surveillance practice to variation in reported incidence. Overall, the identified disease burden and serotype distribution support the need for effective prevention methods in these populations, and the need for community based surveillance studies in rural areas where access to healthcare may be challenging.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 <1%
Unknown 101 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 17%
Student > Master 14 14%
Student > Bachelor 10 10%
Researcher 9 9%
Student > Doctoral Student 6 6%
Other 20 20%
Unknown 26 25%
Readers by discipline Count As %
Medicine and Dentistry 31 30%
Agricultural and Biological Sciences 7 7%
Nursing and Health Professions 6 6%
Immunology and Microbiology 5 5%
Biochemistry, Genetics and Molecular Biology 5 5%
Other 13 13%
Unknown 35 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2016.
All research outputs
#14,176,401
of 22,829,683 outputs
Outputs from BMC Pediatrics
#1,798
of 3,006 outputs
Outputs of similar age
#141,097
of 274,923 outputs
Outputs of similar age from BMC Pediatrics
#39
of 72 outputs
Altmetric has tracked 22,829,683 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,006 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,923 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.