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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The role of IL‐33 and mast cells in allergy and inflammation
|
|---|---|
| Published in |
Clinical and Translational Allergy, September 2015
|
| DOI | 10.1186/s13601-015-0076-5 |
| Pubmed ID | |
| Authors |
Rohit Saluja, Mahejibin Khan, Martin K. Church, Marcus Maurer |
| Abstract |
Interleukin-33 (IL-33) is a member of the interleukin-1 (IL-1) cytokine family. It is preferentially and constitutively expressed in different structural cells such as epithelial cells, endothelial cells, and smooth muscle cells. During necrosis of these cells (after tissue injury or cell damage), the IL-33 that is released may be recognized by different types of immune cells, such as eosinophils, basophils and, especially, mast cells. IL-33 needs the specific receptor ST2 (membrane-bound receptor) and Interleukin-1 receptor accessory protein heterodimer for its binding, which instigates the production of different types of cytokines and chemokines that have crucial roles in the exacerbation of allergic diseases and inflammation. IL-33 and mast cells have been influentially associated to the pathophysiology of allergic diseases and inflammation. IL-33 is a crucial regulator of mast cell functions and might be an attractive therapeutic target for the treatment of allergic and inflammatory diseases. In this review, we summarize the current knowledge regarding the roles of IL-33 and mast cells in the pathogenesis of allergies and inflammation. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 20% |
| Austria | 1 | 10% |
| Romania | 1 | 10% |
| Switzerland | 1 | 10% |
| United States | 1 | 10% |
| Australia | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 50% |
| Practitioners (doctors, other healthcare professionals) | 3 | 30% |
| Scientists | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 194 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 192 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 20% |
| Student > Master | 28 | 14% |
| Researcher | 25 | 13% |
| Student > Bachelor | 18 | 9% |
| Student > Doctoral Student | 13 | 7% |
| Other | 28 | 14% |
| Unknown | 43 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 35 | 18% |
| Medicine and Dentistry | 33 | 17% |
| Immunology and Microbiology | 30 | 15% |
| Biochemistry, Genetics and Molecular Biology | 25 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 5% |
| Other | 9 | 5% |
| Unknown | 53 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2016.
All research outputs
#2,714,790
of 25,374,647 outputs
Outputs from Clinical and Translational Allergy
#151
of 756 outputs
Outputs of similar age
#36,026
of 286,197 outputs
Outputs of similar age from Clinical and Translational Allergy
#2
of 10 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 756 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,197 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.