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A post-trial survey to assess the impact of dissemination of results and unmasking on participants in a 13-year randomised controlled trial on age-related cataract

Overview of attention for article published in Trials, June 2011
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Title
A post-trial survey to assess the impact of dissemination of results and unmasking on participants in a 13-year randomised controlled trial on age-related cataract
Published in
Trials, June 2011
DOI 10.1186/1745-6215-12-148
Pubmed ID
Authors

Sally L Williams, Luigina Ferrigno, Giovanni Maraini, Francesco Rosmini, Robert D Sperduto

Abstract

The Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract was designed to assess the impact of a multivitamin-mineral supplement on age-related cataract. Trial results showed evidence of a beneficial effect of the supplement on all types of cataract combined, opposite effects on two of the three types of cataract (beneficial for nuclear opacities and harmful for posterior sub-capsular opacities) and no statistically significant effect on cortical opacities. No treatment recommendations were made. A post-trial survey was conducted on 817 surviving elderly participants to assess their satisfaction, their understanding of treatment assignment to supplement or placebo and the success of masking.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 3%
Canada 1 3%
Unknown 29 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 19%
Student > Ph. D. Student 4 13%
Student > Doctoral Student 3 10%
Student > Master 3 10%
Student > Postgraduate 2 6%
Other 6 19%
Unknown 7 23%
Readers by discipline Count As %
Medicine and Dentistry 6 19%
Psychology 5 16%
Nursing and Health Professions 3 10%
Veterinary Science and Veterinary Medicine 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 6 19%
Unknown 9 29%