Title |
A post-trial survey to assess the impact of dissemination of results and unmasking on participants in a 13-year randomised controlled trial on age-related cataract
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Published in |
Trials, June 2011
|
DOI | 10.1186/1745-6215-12-148 |
Pubmed ID | |
Authors |
Sally L Williams, Luigina Ferrigno, Giovanni Maraini, Francesco Rosmini, Robert D Sperduto |
Abstract |
The Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract was designed to assess the impact of a multivitamin-mineral supplement on age-related cataract. Trial results showed evidence of a beneficial effect of the supplement on all types of cataract combined, opposite effects on two of the three types of cataract (beneficial for nuclear opacities and harmful for posterior sub-capsular opacities) and no statistically significant effect on cortical opacities. No treatment recommendations were made. A post-trial survey was conducted on 817 surviving elderly participants to assess their satisfaction, their understanding of treatment assignment to supplement or placebo and the success of masking. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 3% |
Canada | 1 | 3% |
Unknown | 29 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 19% |
Student > Ph. D. Student | 4 | 13% |
Student > Doctoral Student | 3 | 10% |
Student > Master | 3 | 10% |
Student > Postgraduate | 2 | 6% |
Other | 6 | 19% |
Unknown | 7 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 19% |
Psychology | 5 | 16% |
Nursing and Health Professions | 3 | 10% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 6 | 19% |
Unknown | 9 | 29% |