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Risk of endometrial polyps in women with endometriosis: a meta-analysis

Overview of attention for article published in Reproductive Biology and Endocrinology, September 2015
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Title
Risk of endometrial polyps in women with endometriosis: a meta-analysis
Published in
Reproductive Biology and Endocrinology, September 2015
DOI 10.1186/s12958-015-0092-2
Pubmed ID
Authors

Qiao-Mei Zheng, Hong-luan Mao, Yan-Jing Zhao, Jing Zhao, Xuan Wei, Pei-Shu Liu

Abstract

Endometrial polyps (EP) and endometriosis are both estrogen-dependent overgrowths of the endometrium. Several studies have shown a higher frequency of EP in endometriosis patients when compared with women without endometriosis. Therefore, we performed a meta-analysis to investigate the risk of EP in women with endometriosis. This meta-analysis searched for articles published between 1964 and 2014 in PubMed, Embase, and Cochrane Library, as well as in Chinese databases, including CNKI, VIP and Wanfang, regarding the association between endometriosis and EP. Nine cohort studies and one case-control study including 2896 women were included in this meta-analysis. The EP risk was evaluated using relative risk (RR) with a 95 % confidence interval (CI). Heterogeneity, small study effect and publication bias were assessed using Higgins I(2), sensitivity analysis and funnel plots, respectively. The risk of EP increased in women with endometriosis compared with those without endometriosis (the pooled RR, 2.81; 95 % CI, 2.48-3.18). No significant heterogeneity, small study effect or publication bias was found. The risk of EP slightly increased in women with endometriosis at stages 2-4 compared with those at stage 1 (Pooled effect size: stage 2 versus stage 1, RR, 1.22, 95 % CI, 1.04 - 1.42; stage 3 versus stage 1, RR, 1.23, 95 % CI, 1.06-1.42; stage 4 versus stage 1, RR, 1.29, 95 % CI, 1.11-1.51; stages 2-4 versus stage 1, RR, 1.24, 95 % CI, 1.10-1.40); however, no significantly different risk of EP in women with endometriosis existed between the other stages. The results suggest that it is important to identify whether patients with endometriosis also have EP and then remove any coexisting EP via hysteroscopy, especially for infertile patients. This process will be clinically helpful to treat endometriosis-related infertility in patients with endometriosis, especially for those with endometriosis that is more serious than stage 1.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 21%
Student > Doctoral Student 6 18%
Student > Postgraduate 4 12%
Other 3 9%
Student > Master 3 9%
Other 2 6%
Unknown 8 24%
Readers by discipline Count As %
Medicine and Dentistry 10 30%
Agricultural and Biological Sciences 3 9%
Biochemistry, Genetics and Molecular Biology 3 9%
Engineering 3 9%
Immunology and Microbiology 2 6%
Other 4 12%
Unknown 8 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2016.
All research outputs
#15,348,067
of 22,829,683 outputs
Outputs from Reproductive Biology and Endocrinology
#535
of 974 outputs
Outputs of similar age
#159,364
of 272,394 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#6
of 15 outputs
Altmetric has tracked 22,829,683 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 974 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.0. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,394 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.