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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis
|
|---|---|
| Published in |
Critical Care, August 2018
|
| DOI | 10.1186/s13054-018-2113-y |
| Pubmed ID | |
| Authors |
F. Sanfilippo, C. Corredor, N. Fletcher, L. Tritapepe, F. L. Lorini, A. Arcadipane, A. Vieillard-Baron, M. Cecconi |
| Abstract |
Sepsis-induced myocardial dysfunction is associated with poor outcomes, but traditional measurements of systolic function such as left ventricular ejection fraction (LVEF) do not directly correlate with prognosis. Global longitudinal strain (GLS) utilizing speckle-tracking echocardiography (STE) could be a better marker of intrinsic left ventricular (LV) function, reflecting myocardial deformation rather than displacement and volume changes. We sought to investigate the prognostic value of GLS in patients with sepsis and/or septic shock. We conducted a systematic review (PubMed and Embase up to 26 October 2017) and meta-analysis to investigate the association between GLS and mortality at longest follow up in patients with severe sepsis and/or septic shock. In the primary analysis, we included studies reporting transthoracic echocardiography data on GLS according to mortality. A secondary analysis evaluated the association between LVEF and mortality including data from studies reporting GLS. We included eight studies in the primary analysis with a total of 794 patients (survival 68%, n = 540). We found a significant association between worse LV function and GLS values and mortality: standard mean difference (SMD) - 0.26; 95% confidence interval (CI) - 0.47, - 0.04; p = 0.02 (low heterogeneity, I2 = 43%). No significant association was found between LVEF and mortality in the same population of patients (eight studies; SMD, 0.02; 95% CI - 0.14, 0.17; p = 0.83; no heterogeneity, I2 = 3%). Worse GLS (less negative) values are associated with higher mortality in patients with severe sepsis or septic shock, while such association is not valid for LVEF. More critical care research is warranted to confirm the better ability of STE in demonstrating underlying intrinsic myocardial disease compared to LVEF. |
X Demographics
The data shown below were collected from the profiles of 136 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 15 | 11% |
| United Kingdom | 14 | 10% |
| Mexico | 11 | 8% |
| Colombia | 6 | 4% |
| Malaysia | 5 | 4% |
| Ecuador | 4 | 3% |
| Spain | 4 | 3% |
| Argentina | 3 | 2% |
| Australia | 3 | 2% |
| Other | 29 | 21% |
| Unknown | 42 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 92 | 68% |
| Practitioners (doctors, other healthcare professionals) | 24 | 18% |
| Scientists | 13 | 10% |
| Science communicators (journalists, bloggers, editors) | 7 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 129 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 19 | 15% |
| Researcher | 13 | 10% |
| Student > Doctoral Student | 10 | 8% |
| Student > Ph. D. Student | 9 | 7% |
| Student > Postgraduate | 9 | 7% |
| Other | 28 | 22% |
| Unknown | 41 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 67 | 52% |
| Nursing and Health Professions | 5 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Agricultural and Biological Sciences | 2 | 2% |
| Computer Science | 1 | <1% |
| Other | 6 | 5% |
| Unknown | 46 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 88. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2023.
All research outputs
#489,084
of 25,698,912 outputs
Outputs from Critical Care
#287
of 6,603 outputs
Outputs of similar age
#10,344
of 342,056 outputs
Outputs of similar age from Critical Care
#4
of 51 outputs
Altmetric has tracked 25,698,912 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,603 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,056 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.