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Summation of connectivity strengths in the visual cortex reveals stability of neuronal microcircuits after plasticity

Overview of attention for article published in BMC Neuroscience, October 2015
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Title
Summation of connectivity strengths in the visual cortex reveals stability of neuronal microcircuits after plasticity
Published in
BMC Neuroscience, October 2015
DOI 10.1186/s12868-015-0203-1
Pubmed ID
Authors

Lyes Bachatene, Vishal Bharmauria, Sarah Cattan, Nayan Chanauria, Jean Rouat, Stéphane Molotchnikoff

Abstract

Within sensory systems, neurons are continuously affected by environmental stimulation. Recently, we showed that, on cell-pair basis, visual adaptation modulates the connectivity strength between similarly tuned neurons to orientation and we suggested that, on a larger scale, the connectivity strength between neurons forming sub-networks could be maintained after adaptation-induced-plasticity. In the present paper, based on the summation of the connectivity strengths, we sought to examine how, within cell-assemblies, functional connectivity is regulated during an exposure-based adaptation. Using intrinsic optical imaging combined with electrophysiological recordings following the reconfiguration of the maps of the primary visual cortex by long stimulus exposure, we found that within functionally connected cells, the summed connectivity strengths remain almost equal although connections among individual pairs are modified. Neuronal selectivity appears to be strongly associated with neuronal connectivity in a "homeodynamic" manner which maintains the stability of cortical functional relationships after experience-dependent plasticity. Our results support the "homeostatic plasticity concept" giving new perspectives on how the summation in visual cortex leads to the stability within labile neuronal ensembles, depending on the newly acquired properties by neurons.

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Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 26%
Student > Ph. D. Student 7 20%
Student > Master 4 11%
Student > Doctoral Student 3 9%
Librarian 2 6%
Other 4 11%
Unknown 6 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 23%
Neuroscience 8 23%
Engineering 3 9%
Medicine and Dentistry 3 9%
Physics and Astronomy 2 6%
Other 4 11%
Unknown 7 20%