MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design

RT @NCIgenomics: Study predicts neoantigen peptides presented by MHC Class II molecules, finds 54 strong binders and 896 weak binders in 14…

RT @NCIgenomics: Study predicts neoantigen peptides presented by MHC Class II molecules, finds 54 strong binders and 896 weak binders in 14…

$ADXS HOT/NEO average of 124 somatic mutations per NSCLC patient The most commonly mutated genes with predicted neo-antigens are KRAS, TTN, RYR2, MUC16, TP53, USH2A, ZFHX4, KEAP1, STK11, FAT3, NAV3 and EGFR https://t.co/gCDgtCzEc6

RT @NCIgenomics: Study predicts neoantigen peptides presented by MHC Class II molecules, finds 54 strong binders and 896 weak binders in 14…