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Use of parenteral caffeinum natrio-benzoicum: an underestimated risk factor for HCV transmission in China

Overview of attention for article published in BMC Public Health, September 2015
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Title
Use of parenteral caffeinum natrio-benzoicum: an underestimated risk factor for HCV transmission in China
Published in
BMC Public Health, September 2015
DOI 10.1186/s12889-015-2299-8
Pubmed ID
Authors

Hongqin Xu, Ge Yu, Haibo Sun, Juan Lv, Moli Wang, Fei Kong, Mingyuan Zhang, Xiumei Chi, Xiaomei Wang, Ruihong Wu, Xiuzhu Gao, Jin Zhong, Bing Sun, Jing Jiang, Yu Pan, Junqi Niu

Abstract

Fuyu city in China has a high prevalence of hepatitis C virus (HCV) infection resulting in a high morbidity and mortality from chronic liver disease and hepatocellular carcinoma. This study was conducted to identify the risk factors for HCV infection in Fuyu city. Recruitment of study subjects involved a cross-sectional survey using non-random, convenience sampling. Information on demographic variables, risk factors for HCV infection, clinical manifestations, behavioral practices and family history was collected by administering a questionnaire. Anti-HCV antibody was detected using Abbott ARCHITECT i2000SR. HCV infection was confirmed by HCV-RNA testing by the Roche Taqman HCV test. Univariate and multivariate analyses were performed to identify the factors associated with HCV infection. Out of 3,228 persons that participated in the survey, 3,219 were enrolled in the study. The prevalence of HCV infection was 42.1 % (1355/3219). Among 734 patients with chronic HCV infection whose HCV-RNA genotyping was performed, genotype 1b was the most common (58.0 %), followed by genotype 2a (40.2 %), while co-infection with genotypes 1b and 2a was detected in 1.8 % of the subjects. On univariate analysis, male gender, older age, parenteral caffeinum natrio-benzoicum and share syringes (PCNBSS), and nine other factors were significantly associated with HCV infection. After adjusting for potential confounders, male gender, old age, cigarette smoking, lower education level, history of blood transfusion, blood donation, prior dental surgery, and PCNBSS were found to be independently associated with HCV infection. The prevalence of HCV infection is likely to be high among residents in Fuyu and we observed that genotypes 1b and 2a dominated in the city. Our findings support the hypothesis that PCNBSS which became endemic in Fuyu city during 1970s-1980s is strongly associated with HCV positivity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 50 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 16%
Researcher 6 12%
Other 4 8%
Student > Master 3 6%
Student > Ph. D. Student 3 6%
Other 5 10%
Unknown 21 42%
Readers by discipline Count As %
Medicine and Dentistry 15 30%
Nursing and Health Professions 2 4%
Agricultural and Biological Sciences 2 4%
Unspecified 1 2%
Computer Science 1 2%
Other 5 10%
Unknown 24 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2016.
All research outputs
#18,429,163
of 22,830,751 outputs
Outputs from BMC Public Health
#12,857
of 14,871 outputs
Outputs of similar age
#196,555
of 273,245 outputs
Outputs of similar age from BMC Public Health
#245
of 287 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
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