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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis
|
|---|---|
| Published in |
Journal of Neuroinflammation, November 2011
|
| DOI | 10.1186/1742-2094-8-149 |
| Pubmed ID | |
| Authors |
Noemí Virgili, Juan F Espinosa-Parrilla, Pilar Mancera, Andrea Pastén-Zamorano, Javier Gimeno-Bayon, Manuel J Rodríguez, Nicole Mahy, Marco Pugliese |
| Abstract |
Multiple Sclerosis (MS) is an acquired inflammatory demyelinating disorder of the central nervous system (CNS) and is the leading cause of nontraumatic disability among young adults. Activated microglial cells are important effectors of demyelination and neurodegeneration, by secreting cytokines and others neurotoxic agents. Previous studies have demonstrated that microglia expresses ATP-sensitive potassium (KATP) channels and its pharmacological activation can provide neuroprotective and anti-inflammatory effects. In this study, we have examined the effect of oral administration of KATP channel opener diazoxide on induced experimental autoimmune encephalomyelitis (EAE), a mouse model of MS. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Spain | 2 | 3% |
| France | 1 | 1% |
| India | 1 | 1% |
| Japan | 1 | 1% |
| Luxembourg | 1 | 1% |
| Unknown | 68 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 20% |
| Student > Bachelor | 10 | 13% |
| Researcher | 9 | 12% |
| Student > Master | 6 | 8% |
| Student > Postgraduate | 5 | 7% |
| Other | 14 | 18% |
| Unknown | 17 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 22% |
| Agricultural and Biological Sciences | 13 | 17% |
| Nursing and Health Professions | 5 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Neuroscience | 4 | 5% |
| Other | 13 | 17% |
| Unknown | 20 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2011.
All research outputs
#14,594,550
of 22,656,971 outputs
Outputs from Journal of Neuroinflammation
#1,630
of 2,602 outputs
Outputs of similar age
#93,452
of 141,800 outputs
Outputs of similar age from Journal of Neuroinflammation
#12
of 21 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,602 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,800 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.