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Septic acute kidney injury: hemodynamic syndrome, inflammatory disorder, or both?

Overview of attention for article published in Critical Care, November 2011
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Title
Septic acute kidney injury: hemodynamic syndrome, inflammatory disorder, or both?
Published in
Critical Care, November 2011
DOI 10.1186/cc10525
Pubmed ID
Authors

Miklos Lipcsey, Rinaldo Bellomo

Abstract

Septic acute kidney injury (S-AKI) is the most common cause of kidney injury in the ICU. Decreased renal blood flow and inflammation have both been suggested as mechanisms of S-AKI. Benes and colleagues present a study of S-AKI in which sepsis is induced by fecal peritonitis and bacterial infusion. In this study, although decreased renal blood flow and increased renal vascular resistance were present in some of the animals that developed S-AKI, inflammatory activation without decreased renal blood flow and increased renal vascular resistance was seen in other animals. Systemic hemodynamic findings provided little information on renal hemodynamics or risk of S-AKI. The study highlights the extraordinary complexity of S-AKI and the need for clinicians to recognize our limited understanding of its pathogenesis and the weakness of the decreased perfusion paradigm as the sole explanation for the loss of renal function seen in severe sepsis.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Other 6 13%
Student > Ph. D. Student 5 11%
Student > Doctoral Student 4 9%
Student > Postgraduate 4 9%
Other 12 27%
Unknown 5 11%
Readers by discipline Count As %
Medicine and Dentistry 36 80%
Agricultural and Biological Sciences 2 4%
Nursing and Health Professions 1 2%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2011.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from Critical Care
#5,469
of 6,554 outputs
Outputs of similar age
#170,259
of 243,921 outputs
Outputs of similar age from Critical Care
#42
of 74 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,921 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.