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Postoperative complications affect early recurrence of hepatocellular carcinoma after curative resection

Overview of attention for article published in BMC Cancer, October 2015
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Title
Postoperative complications affect early recurrence of hepatocellular carcinoma after curative resection
Published in
BMC Cancer, October 2015
DOI 10.1186/s12885-015-1720-0
Pubmed ID
Authors

Yan-Ming Zhou, Xiao-Feng Zhang, Bin Li, Cheng-Jun Sui, Jia-Mei Yang

Abstract

Postoperative recurrence remains the major cause of death after curative resection for hepatocellular carcinoma (HCC). This study was conducted to evaluate the impact of postoperative complications on HCC recurrence after curative resection. The postoperative outcomes of 274 HCC patients who underwent curative resection were analysed retrospectively. Of the 247 HCC patients, 103 (37.6 %) patients developed postoperative complications. The occurrence of postoperative complications was found to be associated with a significantly higher tumor recurrence (76.2 % vs. 56.6 %, P = 0.002) and a lower 5-year overall survival rate (27.7 % vs. 42.1 %; P = 0.037) as compared with those without complications. Regarding the recurrence pattern, early recurrence (≤2 years) was more frequently seen in patients with complications than that in patients without complications (54.5 % vs.38.6 %; P = 0.011). Multivariate analysis indicated that postoperative complications occurrence was an independent risk factor for early recurrence (odds ratio [OR] 2.223; 95 % confidence intervals [95 % CI] 1.161-4.258, P = 0.016) and poor overall survival (OR 1.413; 95 % CI, 1.012-1.971, P = 0.042). The results of the present study indicate that the occurrence of postoperative complications is a predictive factor for HCC recurrence after curative hepatectomy, especially for early recurrence.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Other 6 32%
Student > Doctoral Student 3 16%
Student > Master 2 11%
Researcher 2 11%
Student > Ph. D. Student 2 11%
Other 3 16%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 10 53%
Biochemistry, Genetics and Molecular Biology 2 11%
Business, Management and Accounting 1 5%
Immunology and Microbiology 1 5%
Agricultural and Biological Sciences 1 5%
Other 0 0%
Unknown 4 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2016.
All research outputs
#15,357,612
of 23,613,071 outputs
Outputs from BMC Cancer
#3,797
of 8,487 outputs
Outputs of similar age
#156,570
of 280,498 outputs
Outputs of similar age from BMC Cancer
#94
of 231 outputs
Altmetric has tracked 23,613,071 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,487 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,498 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 231 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.