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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Strategies to improve the immunosuppressive properties of human mesenchymal stem cells
|
|---|---|
| Published in |
Stem Cell Research & Therapy, October 2015
|
| DOI | 10.1186/s13287-015-0178-y |
| Pubmed ID | |
| Authors |
Myoung Woo Lee, Somi Ryu, Dae Seong Kim, Ki Woong Sung, Hong Hoe Koo, Keon Hee Yoo |
| Abstract |
Mesenchymal stem cells (MSCs) are of particular interest for the treatment of immune-related diseases because of their immunosuppressive capacities. However, few clinical trials of MSCs have yielded satisfactory results. A number of clinical trials using MSCs are currently in progress worldwide. Unfortunately, protocols and methods, including optimized culture conditions for the harvest of MSCs, have not been standardized. In this regard, complications in the ex vivo expansion of MSCs and MSC heterogeneity have been implicated in the failure of clinical trials. In this review, potential strategies to obtain MSCs with improved immunosuppressive properties and the potential roles of specific immunomodulatory genes, which are differentially upregulated in certain culture conditions, will be discussed. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Russia | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| France | 1 | 2% |
| Germany | 1 | 2% |
| Unknown | 60 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 33% |
| Researcher | 14 | 22% |
| Student > Doctoral Student | 7 | 11% |
| Student > Master | 6 | 9% |
| Student > Bachelor | 2 | 3% |
| Other | 7 | 11% |
| Unknown | 7 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 22% |
| Biochemistry, Genetics and Molecular Biology | 10 | 16% |
| Medicine and Dentistry | 6 | 9% |
| Engineering | 5 | 8% |
| Immunology and Microbiology | 4 | 6% |
| Other | 17 | 27% |
| Unknown | 8 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2022.
All research outputs
#3,991,574
of 22,994,508 outputs
Outputs from Stem Cell Research & Therapy
#370
of 2,429 outputs
Outputs of similar age
#53,386
of 278,591 outputs
Outputs of similar age from Stem Cell Research & Therapy
#14
of 63 outputs
Altmetric has tracked 22,994,508 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,429 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,591 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.