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Remission of irreversible aripiprazole-induced tardive dystonia with clozapine: a case report

Overview of attention for article published in BMC Psychiatry, October 2015
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  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

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1 patent
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1 Facebook page
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1 Redditor

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44 Mendeley
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Title
Remission of irreversible aripiprazole-induced tardive dystonia with clozapine: a case report
Published in
BMC Psychiatry, October 2015
DOI 10.1186/s12888-015-0644-1
Pubmed ID
Authors

Soohyun Joe, Jangho Park, Jongseok Lim, Choongman Park, Joonho Ahn

Abstract

Aripiprazole can cause irreversible tardive dystonia in some individuals, and additional intervention is sometimes needed. Here, we report the first case of aripiprazole-induced irreversible tardive dystonia in which complete recovery of motor function was achieved using the antipsychotic drug clozapine. A 24-year-old man with bipolar disorder was treated with aripiprazole and gradually developed tardive dystonia. Thorough medical and neurological examinations were performed to rule out other possible causes of tardive dystonia. Clozapine was administered when the patient did not improve following long-term withdrawal of aripiprazole or adjuvant medications. Before administration of clozapine, the patient was experiencing severe dystonia as assessed by the Extrapyramidal Symptom Rating Scale. Dystonic symptoms began to improve about 1 month after starting administration of clozapine and were completely resolved 3 months after clozapine administration. Clinicians should note the risk of aripiprazole-induced tardive dystonia and consider clozapine as an alternative and effective treatment modality in cases of irreversible tardive dystonia, particularly when concomitant treatment of psychotic symptoms is required.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 16%
Other 5 11%
Professor > Associate Professor 4 9%
Student > Doctoral Student 3 7%
Student > Ph. D. Student 3 7%
Other 11 25%
Unknown 11 25%
Readers by discipline Count As %
Medicine and Dentistry 14 32%
Psychology 3 7%
Nursing and Health Professions 3 7%
Linguistics 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 6 14%
Unknown 14 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2021.
All research outputs
#6,426,255
of 22,830,751 outputs
Outputs from BMC Psychiatry
#2,225
of 4,692 outputs
Outputs of similar age
#80,920
of 283,771 outputs
Outputs of similar age from BMC Psychiatry
#34
of 87 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 4,692 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,771 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.