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Endothelial cell control of thrombosis

Overview of attention for article published in BMC Cardiovascular Disorders, October 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#8 of 1,584)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

twitter
75 tweeters
patent
1 patent

Citations

dimensions_citation
387 Dimensions

Readers on

mendeley
558 Mendeley
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Title
Endothelial cell control of thrombosis
Published in
BMC Cardiovascular Disorders, October 2015
DOI 10.1186/s12872-015-0124-z
Pubmed ID
Authors

Jonathan W. Yau, Hwee Teoh, Subodh Verma

Abstract

Hemostasis encompasses a set of tightly regulated processes that govern blood clotting, platelet activation, and vascular repair. Upon vascular injury, the hemostatic system initiates a series of vascular events and activates extravascular receptors that act in concert to seal off the damage. Blood clotting is subsequently attenuated by a plethora of inhibitors that prevent excessive clot formation and eventual thrombosis. The endothelium which resides at the interface between the blood and surrounding tissues, serves an integral role in the hemostatic system. Depending on specific tissue needs and local stresses, endothelial cells are capable of evoking either antithrombotic or prothrombotic events. Healthy endothelial cells express antiplatelet and anticoagulant agents that prevent platelet aggregation and fibrin formation, respectively. In the face of endothelial dysfunction, endothelial cells trigger fibrin formation, as well as platelet adhesion and aggregation. Finally, endothelial cells release pro-fibrinolytic agents that initiate fibrinolysis to degrade the clot. Taken together, a functional endothelium is essential to maintain hemostasis and prevent thrombosis. Thus, a greater understanding into the role of the endothelium can provide new avenues for exploration and novel therapies for the management of thromboembolisms.

Twitter Demographics

The data shown below were collected from the profiles of 75 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 558 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Spain 1 <1%
South Africa 1 <1%
Brazil 1 <1%
Unknown 554 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 109 20%
Student > Bachelor 86 15%
Student > Master 65 12%
Researcher 61 11%
Student > Doctoral Student 29 5%
Other 82 15%
Unknown 126 23%
Readers by discipline Count As %
Medicine and Dentistry 123 22%
Biochemistry, Genetics and Molecular Biology 104 19%
Agricultural and Biological Sciences 43 8%
Engineering 40 7%
Immunology and Microbiology 16 3%
Other 71 13%
Unknown 161 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 63. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2022.
All research outputs
#565,628
of 22,618,386 outputs
Outputs from BMC Cardiovascular Disorders
#8
of 1,584 outputs
Outputs of similar age
#10,066
of 304,036 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#1
of 87 outputs
Altmetric has tracked 22,618,386 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,584 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,036 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.