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The spliceosome, a potential Achilles heel of MYC-driven tumors

Overview of attention for article published in Genome Medicine, October 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

Mentioned by

news
1 news outlet
twitter
11 X users
facebook
1 Facebook page

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
69 Mendeley
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Title
The spliceosome, a potential Achilles heel of MYC-driven tumors
Published in
Genome Medicine, October 2015
DOI 10.1186/s13073-015-0234-3
Pubmed ID
Authors

Olga Anczuków, Adrian R. Krainer

Abstract

Alterations in RNA splicing are frequent in human tumors. Two recent studies of lymphoma and breast cancer have identified components of the spliceosome - the core splicing machinery - that are essential for malignant transformation driven by the transcription factor MYC. These findings provide a direct link between MYC and RNA splicing deregulation, and raise the exciting possibility of targeting spliceosome components in MYC-driven tumors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 69 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 28%
Researcher 11 16%
Student > Bachelor 10 14%
Professor 6 9%
Student > Master 6 9%
Other 7 10%
Unknown 10 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 22 32%
Agricultural and Biological Sciences 20 29%
Medicine and Dentistry 7 10%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Computer Science 1 1%
Other 6 9%
Unknown 9 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2015.
All research outputs
#2,041,538
of 22,830,751 outputs
Outputs from Genome Medicine
#462
of 1,442 outputs
Outputs of similar age
#31,191
of 283,279 outputs
Outputs of similar age from Genome Medicine
#13
of 30 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,442 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,279 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.