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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Myocardial native T2 measurement to differentiate light-chain and transthyretin cardiac amyloidosis and assess prognosis
|
|---|---|
| Published in |
Critical Reviews in Diagnostic Imaging, August 2018
|
| DOI | 10.1186/s12968-018-0478-3 |
| Pubmed ID | |
| Authors |
Fourat Ridouani, Thibaud Damy, Vania Tacher, Haytham Derbel, François Legou, Islem Sifaoui, Etienne Audureau, Diane Bodez, Alain Rahmouni, Jean-François Deux |
| Abstract |
To assess the diagnostic and prognosis value of myocardial native T2 measurement in the distinction between Light-chain (AL) and Transthyretin (ATTR) cardiac amyloidosis (CA). Forty-four patients with CA (24 AL; 20 ATTR) and 40 healthy subjects underwent 1.5 T cardiovascular magnetic resonance (CMR). They all underwent T1 and T2 mapping (modified Look-Locker inversion recovery), cine and late gadolinium enhancement (LGE) imaging. The Query Amyloid Late Enhancement (QALE) score, myocardial native T2, T1 and extra cellular volume fraction (ECV) were calculated for all patients. Of the 44 patients, 36 (82%) exhibited enhancement on LGE images. Mean QALE score of AL (7.9 ± 6) and ATTR (10.5 ± 5) patients were similar (p = 0.6). Myocardial native T2 was significantly (p < 0.0001) higher in AL (63.2 ± 4.7 ms) than in ATTR (56.2 ± 3.1 ms) patients, and both higher (p < 0.001) than healthy subjects (51.1 ± 3.1 ms). Myocardial native T2 was highly correlated with myocardial native T1 (Spearman's rho = 0.79; p < 0.001) and exhibited higher diagnostic performance than T1 to separate AL and ATTR patients: the area under curve (AUC) of T2 was 0.94 (95% CI: 0.86-1, p < 0.001) and the AUC of T1 was 0.77 (95% CI: 0.62-0.91, p = 0.03). Myocardial native T2 did not impact overall survival in patients (HR 1.03 (0.94-1.12); p = 0.53) in contrast to ECV that was the best predictor of outcome (HR 1.66 per 0.1 increase in ECV (1.24-2.22); p = 0.0006). Myocardial native T2 significantly is increased in CA, especially in AL patients in comparison to ATTR patients. Myocardial native T2 does not impact survival in CA patients in contrast to ECV that was the best predictor of outcome. Trial Registration and unique number: CNIL cardio 1778041. Date of registration: 20 December 2012. |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 36% |
| United Kingdom | 3 | 12% |
| Peru | 1 | 4% |
| France | 1 | 4% |
| Saudi Arabia | 1 | 4% |
| Germany | 1 | 4% |
| Unknown | 9 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 60% |
| Scientists | 5 | 20% |
| Practitioners (doctors, other healthcare professionals) | 4 | 16% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 82 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 11% |
| Other | 8 | 10% |
| Student > Ph. D. Student | 8 | 10% |
| Student > Postgraduate | 7 | 9% |
| Student > Doctoral Student | 5 | 6% |
| Other | 18 | 22% |
| Unknown | 27 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 45% |
| Unspecified | 2 | 2% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Engineering | 2 | 2% |
| Social Sciences | 2 | 2% |
| Other | 6 | 7% |
| Unknown | 31 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2018.
All research outputs
#2,671,769
of 25,523,622 outputs
Outputs from Critical Reviews in Diagnostic Imaging
#131
of 1,379 outputs
Outputs of similar age
#50,226
of 325,339 outputs
Outputs of similar age from Critical Reviews in Diagnostic Imaging
#9
of 24 outputs
Altmetric has tracked 25,523,622 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,379 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,339 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.