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miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells

Overview of attention for article published in Breast Cancer Research, November 2011
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Title
miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells
Published in
Breast Cancer Research, November 2011
DOI 10.1186/bcr3059
Pubmed ID
Authors

Yee-Ming Lee, Jen-Yi Lee, Chao-Chi Ho, Qi-Sheng Hong, Sung-Liang Yu, Chii-Ruey Tzeng, Pan-Chyr Yang, Huei-Wen Chen

Abstract

Estrogen is involved in several physiological and pathological processes through estrogen receptor (ER)-mediated transcriptional gene regulation. miRNAs (miRs), which are noncoding RNA genes, may respond to estrogen and serve as posttranscriptional regulators in tumorigenic progression, especially in breast cancer; however, only limited information about this possibility is available. In the present study, we identified the estrogen-regulated miR-34b and investigated its functional role in breast cancer progression.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
China 1 2%
Canada 1 2%
Unknown 60 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 14%
Student > Bachelor 9 14%
Student > Master 7 11%
Student > Doctoral Student 5 8%
Researcher 5 8%
Other 16 25%
Unknown 12 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 22%
Medicine and Dentistry 14 22%
Agricultural and Biological Sciences 13 21%
Engineering 3 5%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 17 27%