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Apathy is associated with faster global cognitive decline and early nursing home admission in dementia with Lewy bodies

Overview of attention for article published in Alzheimer's Research & Therapy, August 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Average Attention Score compared to outputs of the same age and source

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1 news outlet
blogs
1 blog
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2 X users

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20 Dimensions

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68 Mendeley
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Title
Apathy is associated with faster global cognitive decline and early nursing home admission in dementia with Lewy bodies
Published in
Alzheimer's Research & Therapy, August 2018
DOI 10.1186/s13195-018-0416-5
Pubmed ID
Authors

Monica H. Breitve, Kolbjørn Brønnick, Luiza J. Chwiszczuk, Minna J. Hynninen, Dag Aarsland, Arvid Rongve

Abstract

Little is known about the consequences of apathy in dementia with Lewy bodies (DLB), because previous research on apathy in dementia focused mainly on Alzheimer's disease (AD). In this longitudinal study, we included patients with AD (n = 128) and patients with DLB (n = 81). At baseline, we analyzed the associations between apathy and cognition in the total sample and in AD and DLB separately. Generalized linear mixed models were used to investigate the association between apathy and Mini Mental State Examination (MMSE) over 4 years, and the Kaplan-Meier method was used to assess the association between apathy and survival or nursing home admission. In patients with DLB, apathy was associated with a faster global cognitive decline (MMSE) over 4 years. Patients with DLB and apathy had shorter time until nursing home admission than DLB patients without apathy and patients with AD, regardless of apathy. At baseline, patients with apathy had decreased performance on the Stroop color test and a composite executive function score. Neurocognition was unaffected by apathy in AD, but DLB patients with apathy had more verbal learning difficulties. Apathy seems to be associated with more serious symptomatology in DLB than in AD. It is important to focus on apathy in dementia because it is one of the most prevalent and disturbing behavioral and psychological symptoms.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 68 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 15%
Student > Ph. D. Student 9 13%
Student > Master 7 10%
Student > Bachelor 4 6%
Student > Postgraduate 3 4%
Other 8 12%
Unknown 27 40%
Readers by discipline Count As %
Medicine and Dentistry 11 16%
Psychology 10 15%
Neuroscience 4 6%
Social Sciences 4 6%
Nursing and Health Professions 3 4%
Other 6 9%
Unknown 30 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2019.
All research outputs
#2,084,419
of 23,509,982 outputs
Outputs from Alzheimer's Research & Therapy
#444
of 1,292 outputs
Outputs of similar age
#44,710
of 334,267 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#28
of 40 outputs
Altmetric has tracked 23,509,982 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,292 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,267 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.