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Sox7 is dispensable for primitive endoderm differentiation from mouse ES cells

Overview of attention for article published in BMC Developmental Biology, October 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users

Citations

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10 Dimensions

Readers on

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38 Mendeley
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Title
Sox7 is dispensable for primitive endoderm differentiation from mouse ES cells
Published in
BMC Developmental Biology, October 2015
DOI 10.1186/s12861-015-0079-4
Pubmed ID
Authors

Masaki Kinoshita, Daisuke Shimosato, Mariko Yamane, Hitoshi Niwa

Abstract

Primitive endoderm is a cell lineage segregated from the epiblast in the blastocyst and gives rise to parietal and visceral endoderm. Sox7 is a member of the SoxF gene family that is specifically expressed in primitive endoderm in the late blastocyst, although its function in this cell lineage remains unclear. Here we characterize the function of Sox7 in primitive endoderm differentiation using mouse embryonic stem (ES) cells as a model system. We show that ectopic expression of Sox7 in ES cells has a marginal effect on triggering differentiation into primitive endoderm-like cells. We also show that targeted disruption of Sox7 in ES cells does not affect differentiation into primitive endoderm cells in embryoid body formation as well as by forced expression of Gata6. These data indicate that Sox7 function is supplementary and not essential for this differentiation from ES cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Unknown 37 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 26%
Student > Ph. D. Student 9 24%
Researcher 6 16%
Student > Bachelor 3 8%
Student > Postgraduate 2 5%
Other 3 8%
Unknown 5 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 42%
Agricultural and Biological Sciences 14 37%
Arts and Humanities 1 3%
Social Sciences 1 3%
Medicine and Dentistry 1 3%
Other 0 0%
Unknown 5 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2015.
All research outputs
#3,790,239
of 22,831,537 outputs
Outputs from BMC Developmental Biology
#55
of 369 outputs
Outputs of similar age
#52,050
of 280,050 outputs
Outputs of similar age from BMC Developmental Biology
#2
of 13 outputs
Altmetric has tracked 22,831,537 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 369 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,050 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.