Title |
Diagnosis and management of inhalation injury: an updated review
|
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Published in |
Critical Care, December 2015
|
DOI | 10.1186/s13054-015-1077-4 |
Pubmed ID | |
Authors |
Patrick F. Walker, Michelle F. Buehner, Leslie A. Wood, Nathan L. Boyer, Ian R. Driscoll, Jonathan B. Lundy, Leopoldo C. Cancio, Kevin K. Chung |
Abstract |
In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest computed tomography may allow for a more nuanced evaluation of inhalation injury and enhanced ability to prognosticate. Supportive respiratory care remains essential in managing inhalation injury. Adjuncts still lacking definitive evidence of efficacy include bronchodilators, mucolytic agents, inhaled anticoagulants, nonconventional ventilator modes, prone positioning, and extracorporeal membrane oxygenation. Recent research focusing on molecular mechanisms involved in inhalation injury has increased the number of potential therapies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 16 | 15% |
United States | 10 | 10% |
Spain | 7 | 7% |
Mexico | 4 | 4% |
Italy | 3 | 3% |
Australia | 2 | 2% |
Ecuador | 2 | 2% |
Canada | 2 | 2% |
Malaysia | 2 | 2% |
Other | 13 | 12% |
Unknown | 44 | 42% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 71 | 68% |
Practitioners (doctors, other healthcare professionals) | 20 | 19% |
Scientists | 8 | 8% |
Science communicators (journalists, bloggers, editors) | 6 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Mexico | 1 | <1% |
Czechia | 1 | <1% |
France | 1 | <1% |
Unknown | 357 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 60 | 17% |
Student > Bachelor | 48 | 13% |
Student > Postgraduate | 43 | 12% |
Student > Master | 33 | 9% |
Researcher | 32 | 9% |
Other | 67 | 19% |
Unknown | 78 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 202 | 56% |
Nursing and Health Professions | 31 | 9% |
Engineering | 9 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 1% |
Agricultural and Biological Sciences | 4 | 1% |
Other | 22 | 6% |
Unknown | 88 | 24% |