Title |
Value of variation index of inferior vena cava diameter in predicting fluid responsiveness in patients with circulatory shock receiving mechanical ventilation: a systematic review and meta-analysis
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Published in |
Critical Care, August 2018
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DOI | 10.1186/s13054-018-2063-4 |
Pubmed ID | |
Authors |
Haijun Huang, Qinkang Shen, Yafen Liu, Hua Xu, Yixin Fang |
Abstract |
Respiratory variations in the inferior vena cava diameter (ΔIVCD) have been studied extensively with respect to their value in predicting fluid responsiveness, but the results are conflicting. The aim of this meta-analysis was to explore the value of ΔIVCD for predicting fluid responsiveness in patients with circulatory shock receiving mechanical ventilation. PubMed, Embase, and the Cochrane Central Register of Controlled Trials were searched up to June 2017. The diagnostic OR (DOR), sensitivity, and specificity were calculated. The summary ROC curve was estimated, and the area under the ROC curve (AUROC) was calculated. Overall, 603 patients were included in this review, 324 (53.7%) of whom were fluid-responsive. The cutoff values of ΔIVCD varied across studies, ranging from 8% to 21%. Heterogeneity between studies was assessed with an overall Q = 0.069, I2 = 0%, and P = 0.483. The pooled sensitivity and specificity for the overall population were 0.69 (95% CI, 0.51-0.83) and 0.80 (95% CI, 0.66-0.89), respectively. The DOR was 9.28 (95% CI, 2.33-36.98). AUROCs were reported in five studies. Overall, the pooled AUROC was 0.82 (95% CI, 0.79-0.85). The findings of this study suggest that the ΔIVCD performed moderately well in predicting fluid responsiveness in patients with circulatory shock receiving mechanical ventilation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Mexico | 9 | 7% |
United Kingdom | 8 | 7% |
United States | 8 | 7% |
Colombia | 7 | 6% |
Italy | 7 | 6% |
Chile | 5 | 4% |
Spain | 4 | 3% |
Ecuador | 3 | 2% |
France | 2 | 2% |
Other | 15 | 12% |
Unknown | 54 | 44% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 94 | 77% |
Practitioners (doctors, other healthcare professionals) | 20 | 16% |
Scientists | 5 | 4% |
Science communicators (journalists, bloggers, editors) | 3 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 84 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 16 | 19% |
Researcher | 10 | 12% |
Student > Ph. D. Student | 8 | 10% |
Student > Postgraduate | 6 | 7% |
Student > Doctoral Student | 5 | 6% |
Other | 21 | 25% |
Unknown | 18 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 52 | 62% |
Nursing and Health Professions | 3 | 4% |
Engineering | 2 | 2% |
Arts and Humanities | 1 | 1% |
Agricultural and Biological Sciences | 1 | 1% |
Other | 3 | 4% |
Unknown | 22 | 26% |