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Gut microbiota and sirtuins in obesity-related inflammation and bowel dysfunction

Overview of attention for article published in Journal of Translational Medicine, November 2011
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Mentioned by

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4 X users

Citations

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25 Dimensions

Readers on

mendeley
148 Mendeley
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1 CiteULike
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Title
Gut microbiota and sirtuins in obesity-related inflammation and bowel dysfunction
Published in
Journal of Translational Medicine, November 2011
DOI 10.1186/1479-5876-9-202
Pubmed ID
Authors

Shaheen E Lakhan, Annette Kirchgessner

Abstract

Obesity is a chronic disease characterized by persistent low-grade inflammation with alterations in gut motility. Motor abnormalities suggest that obesity has effects on the enteric nervous system (ENS), which controls virtually all gut functions. Recent studies have revealed that the gut microbiota can affect obesity and increase inflammatory tone by modulating mucosal barrier function. Furthermore, the observation that inflammatory conditions influence the excitability of enteric neurons may add to the gut dysfunction in obesity. In this article, we discuss recent advances in understanding the role of gut microbiota and inflammation in the pathogenesis of obesity and obesity-related gastrointestinal dysfunction. The potential contribution of sirtuins in protecting or regulating the circuitry of the ENS under inflamed states is also considered.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Malaysia 1 <1%
France 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 143 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 20%
Student > Bachelor 24 16%
Student > Ph. D. Student 21 14%
Student > Master 16 11%
Other 10 7%
Other 23 16%
Unknown 25 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 54 36%
Medicine and Dentistry 19 13%
Biochemistry, Genetics and Molecular Biology 17 11%
Immunology and Microbiology 9 6%
Pharmacology, Toxicology and Pharmaceutical Science 4 3%
Other 15 10%
Unknown 30 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2021.
All research outputs
#15,268,080
of 24,677,985 outputs
Outputs from Journal of Translational Medicine
#1,929
of 4,450 outputs
Outputs of similar age
#162,121
of 249,080 outputs
Outputs of similar age from Journal of Translational Medicine
#31
of 59 outputs
Altmetric has tracked 24,677,985 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,450 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,080 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.