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Evolutionary relationships and diversification of barhl genes within retinal cell lineages

Overview of attention for article published in BMC Ecology and Evolution, November 2011
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Title
Evolutionary relationships and diversification of barhl genes within retinal cell lineages
Published in
BMC Ecology and Evolution, November 2011
DOI 10.1186/1471-2148-11-340
Pubmed ID
Authors

Laura-Nadine Schuhmacher, Shahad Albadri, Mirana Ramialison, Lucia Poggi

Abstract

Basic helix-loop-helix and homeodomain transcription factors have been shown to specify all different neuronal cell subtypes composing the vertebrate retina. The appearance of gene paralogs of such retina-specific transcription factors in lower vertebrates, with differently evolved function and/or conserved non-coding elements, might provide an important source for the generation of neuronal diversity within the vertebrate retinal architecture. In line with this hypothesis, we investigated the evolution of the homeobox Barhl family of transcription factors, barhl1 and barhl2, in the teleost and tetrapod lineages. In tetrapod barhl2, but not barhl1, is expressed in the retina and is important for amacrine cell specification. Zebrafish has three barhl paralogs: barhl1.1, barhl1.2 and barhl2, but their precise spatio-temporal retinal expression, as well as their function is yet unknown.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 8%
United Kingdom 2 5%
Portugal 1 3%
Unknown 34 85%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 30%
Student > Bachelor 8 20%
Student > Master 6 15%
Professor > Associate Professor 6 15%
Researcher 5 13%
Other 2 5%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 65%
Neuroscience 5 13%
Medicine and Dentistry 2 5%
Computer Science 2 5%
Arts and Humanities 1 3%
Other 2 5%
Unknown 2 5%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2011.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from BMC Ecology and Evolution
#2,929
of 3,714 outputs
Outputs of similar age
#171,022
of 245,122 outputs
Outputs of similar age from BMC Ecology and Evolution
#38
of 56 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.