Title |
Pulmonary artery enlargement in schistosomiasis associated pulmonary arterial hypertension
|
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Published in |
BMC Pulmonary Medicine, October 2015
|
DOI | 10.1186/s12890-015-0115-y |
Pubmed ID | |
Authors |
Susana Hoette, Claudia Figueiredo, Bruno Dias, Jose Leonidas Alves-Jr, Francisca Gavilanes, Luis Felipe Prada, Dany Jasinowodolinski, Luciana Tamie Kato Morinaga, Carlos Jardim, Caio Julio Cesar Fernandes, Rogério Souza |
Abstract |
Schistosomiasis associated pulmonary arterial hypertension (Sch-PAH) might represent the most prevalent form of PAH worldwide. In Sch-PAH, the presence of aneurismal dilation of the pulmonary artery has been described, although it is still a matter of debate whether on average the pulmonary artery is more enlarged in Sc-PAH than IPAH. We retrospectively evaluated patients with IPAH (n = 25) and Sch-PAH (n = 22) who underwent computed tomography pulmonary angiogram and right heart catheterization. Sch-PAH patients were older and presented less severe hemodynamic profiles. Main pulmonary artery diameter (MPAD) was greater in Sch-PAH than IPAH (4.5 ± 1.8 vs 3.7 ± 1.1 cm, p = 0.018). For the same level of mean pulmonary artery pressure, the MPAD in Sch-PAH was 0.89 cm larger than in IPAH (Covariance model p = 0.02). This study demonstrated that pulmonary artery enlargement is more pronounced in Sch-PAH than IPAH, independently of mean pulmonary artery pressure level, suggesting that this is more likely a feature of Sch-PAH. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Venezuela, Bolivarian Republic of | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Librarian | 3 | 12% |
Other | 3 | 12% |
Student > Bachelor | 3 | 12% |
Professor | 3 | 12% |
Student > Master | 3 | 12% |
Other | 4 | 16% |
Unknown | 6 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 56% |
Arts and Humanities | 1 | 4% |
Nursing and Health Professions | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Unknown | 8 | 32% |