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Small airway epithelial-C/EBPβ is increased in patients with advanced COPD

Overview of attention for article published in Respiratory Research, January 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)

Mentioned by

twitter
2 tweeters
googleplus
1 Google+ user

Citations

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8 Dimensions

Readers on

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15 Mendeley
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Title
Small airway epithelial-C/EBPβ is increased in patients with advanced COPD
Published in
Respiratory Research, January 2015
DOI 10.1186/s12931-015-0297-0
Pubmed ID
Authors

Michiko Mori, Leif Bjermer, Jonas S Erjefält, Martin R Stampfli, Abraham B Roos

Abstract

The expression of CCAAT/enhancer-binding protein (C/EBP)β in the small airway epithelium of COPD is unknown. C/EBPβ was assessed in peripheral lung tissue of non-smoking/smoking controls and patients with GOLD I-IV COPD by quantitative immunohistochemistry. The expression of C/EBPβ was decreased in smokers compared to never smokers. Furthermore, C/EBPβ was significantly elevated in advanced COPD vs. asymptomatic smokers, and the expression correlated to lung function decline. As C/EBPβ exerts pro-inflammatory effects in the context of cigarette smoke, the elevated C/EBPβ in advanced COPD may be an indication of a breakdown of regulatory mechanisms and excessive inflammation.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 20%
Student > Master 3 20%
Researcher 2 13%
Student > Ph. D. Student 1 7%
Student > Bachelor 1 7%
Other 2 13%
Unknown 3 20%
Readers by discipline Count As %
Medicine and Dentistry 4 27%
Agricultural and Biological Sciences 3 20%
Biochemistry, Genetics and Molecular Biology 2 13%
Immunology and Microbiology 2 13%
Nursing and Health Professions 1 7%
Other 0 0%
Unknown 3 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2015.
All research outputs
#5,701,311
of 10,677,937 outputs
Outputs from Respiratory Research
#722
of 1,236 outputs
Outputs of similar age
#103,586
of 249,141 outputs
Outputs of similar age from Respiratory Research
#33
of 47 outputs
Altmetric has tracked 10,677,937 research outputs across all sources so far. This one is in the 45th percentile – i.e., 45% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,236 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,141 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.