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Progress in mesenchymal stem cell–based therapy for acute liver failure

Overview of attention for article published in Stem Cell Research & Therapy, August 2018
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Mentioned by

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1 Google+ user

Citations

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53 Dimensions

Readers on

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63 Mendeley
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Title
Progress in mesenchymal stem cell–based therapy for acute liver failure
Published in
Stem Cell Research & Therapy, August 2018
DOI 10.1186/s13287-018-0972-4
Pubmed ID
Authors

Yong-Hong Wang, Dong-Bo Wu, Bing Chen, En-Qiang Chen, Hong Tang

Abstract

Acute liver failure is a life-threatening clinical syndrome characterized by rapid development of hepatocellular necrosis leading to high mortality and resource costs. Numerous treatment strategies for acute liver failure simply prevent complications and decelerate disease progression. The only curative treatment for acute liver failure is liver transplantation, but there are many restrictions on the application of liver transplantation. In recent years, a growing number of studies have shown that stem cells can effectively treat acute liver failure. Several types of stem cells have been used to study liver diseases; mesenchymal stem cells are most commonly used because they are easy to obtain and present no ethical problems. The aims of this article are to review the current knowledge regarding therapeutic mechanisms of mesenchymal stem cells in acute liver failure, to discuss recent advancements in preclinical and clinical studies in the treatment of mesenchymal stem cells, and to summarize the methodological improvement of mesenchymal stem cell transplantation in treating liver failure.

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 25%
Student > Master 10 16%
Researcher 6 10%
Student > Ph. D. Student 5 8%
Other 3 5%
Other 10 16%
Unknown 13 21%
Readers by discipline Count As %
Medicine and Dentistry 17 27%
Biochemistry, Genetics and Molecular Biology 12 19%
Agricultural and Biological Sciences 5 8%
Nursing and Health Professions 3 5%
Veterinary Science and Veterinary Medicine 2 3%
Other 7 11%
Unknown 17 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2018.
All research outputs
#8,934,807
of 14,259,883 outputs
Outputs from Stem Cell Research & Therapy
#737
of 1,305 outputs
Outputs of similar age
#163,805
of 273,436 outputs
Outputs of similar age from Stem Cell Research & Therapy
#1
of 1 outputs
Altmetric has tracked 14,259,883 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,305 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,436 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them