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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mutation discovery in mice by whole exome sequencing
|
|---|---|
| Published in |
Genome Biology, September 2011
|
| DOI | 10.1186/gb-2011-12-9-r86 |
| Pubmed ID | |
| Authors |
Heather Fairfield, Griffith J Gilbert, Mary Barter, Rebecca R Corrigan, Michelle Curtain, Yueming Ding, Mark D'Ascenzo, Daniel J Gerhardt, Chao He, Wenhui Huang, Todd Richmond, Lucy Rowe, Frank J Probst, David E Bergstrom, Stephen A Murray, Carol Bult, Joel Richardson, Benjamin T Kile, Ivo Gut, Jorg Hager, Snaevar Sigurdsson, Evan Mauceli, Federica Di Palma, Kerstin Lindblad-Toh, Michael L Cunningham, Timothy C Cox, Monica J Justice, Mona S Spector, Scott W Lowe, Thomas Albert, Leah Rae Donahue, Jeffrey Jeddeloh, Jay Shendure, Laura G Reinholdt |
| Abstract |
We report the development and optimization of reagents for in-solution, hybridization-based capture of the mouse exome. By validating this approach in a multiple inbred strains and in novel mutant strains, we show that whole exome sequencing is a robust approach for discovery of putative mutations, irrespective of strain background. We found strong candidate mutations for the majority of mutant exomes sequenced, including new models of orofacial clefting, urogenital dysmorphology, kyphosis and autoimmune hepatitis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 172 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 4% |
| Sweden | 2 | 1% |
| Spain | 2 | 1% |
| Austria | 1 | <1% |
| India | 1 | <1% |
| Belgium | 1 | <1% |
| Russia | 1 | <1% |
| Australia | 1 | <1% |
| Japan | 1 | <1% |
| Other | 3 | 2% |
| Unknown | 152 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 58 | 34% |
| Student > Ph. D. Student | 35 | 20% |
| Professor > Associate Professor | 13 | 8% |
| Student > Bachelor | 10 | 6% |
| Student > Master | 10 | 6% |
| Other | 31 | 18% |
| Unknown | 15 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 45% |
| Biochemistry, Genetics and Molecular Biology | 37 | 22% |
| Medicine and Dentistry | 20 | 12% |
| Computer Science | 5 | 3% |
| Veterinary Science and Veterinary Medicine | 2 | 1% |
| Other | 12 | 7% |
| Unknown | 18 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2012.
All research outputs
#16,048,318
of 25,374,917 outputs
Outputs from Genome Biology
#4,001
of 4,467 outputs
Outputs of similar age
#92,148
of 137,127 outputs
Outputs of similar age from Genome Biology
#41
of 46 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 137,127 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.