↓ Skip to main content

Gadolinium free cardiovascular magnetic resonance with 2-point Cine balanced steady state free precession

Overview of attention for article published in Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd), October 2015
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

twitter
10 tweeters

Citations

dimensions_citation
19 Dimensions

Readers on

mendeley
44 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Gadolinium free cardiovascular magnetic resonance with 2-point Cine balanced steady state free precession
Published in
Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd), October 2015
DOI 10.1186/s12968-015-0194-1
Pubmed ID
Authors

Tori A. Stromp, Steve W. Leung, Kristin N. Andres, Linyuan Jing, Brandon K. Fornwalt, Richard J. Charnigo, Vincent L. Sorrell, Moriel H. Vandsburger

Abstract

Cardiovascular magnetic resonance (CMR) of ventricular structure and function is widely performed using cine balanced steady state free precession (bSSFP) MRI. The bSSFP signal of myocardium is weighted by magnetization transfer (MT) and T1/T2-relaxation times. In edematous and fibrotic tissues, increased T2 and reduced MT lead to increased signal intensity on images acquired with high excitation flip angles. We hypothesized that acquisition of two differentially MT-weighted bSSFP images (termed 2-point bSSFP) can identify tissue that would enhance with gadolinium similar to standard of care late gadolinium enhancement (LGE). Cine bSSFP images (flip angles of 5° and 45°) and native-T1 and T2 maps were acquired in one mid-ventricular slice in 47 patients referred for CMR and 10 healthy controls. Afterwards, LGE images and post-contrast T1 maps were acquired and gadolinium partition coefficient (GPC) was calculated. Maps of ΔS/So were calculated as (S45-S5)/S5*100 (%), where Sflip_angle is the voxel signal intensity. Twenty three patients demonstrated areas of myocardial hyper-enhancement with LGE. In enhanced regions, ΔS/So, native-T1, T2, and GPC were heightened (p < 0.05 vs. non-enhanced tissues). ΔS/So, native-T1, and T2 all demonstrated association with GPC, however the association was strongest for ΔS/So. Bland-Altman analysis revealed a slight bias towards larger volume of enhancement with ΔS/So compared to LGE, and similar transmurality. Subjective analysis with 2-blinded expert readers revealed agreement between ΔS/So and LGE of 73.4 %, with false positive detection of 16.7 % and false negative detection of 15.2 %. Gadolinium free 2-point bSSFP identified tissue that enhances at LGE with strong association to GPC. Our results suggest that with further development, MT-weighted CMR could be used similar to LGE for diagnostic imaging.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
United States 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 23%
Student > Ph. D. Student 7 16%
Other 5 11%
Student > Master 5 11%
Professor 3 7%
Other 10 23%
Unknown 4 9%
Readers by discipline Count As %
Medicine and Dentistry 19 43%
Engineering 8 18%
Nursing and Health Professions 2 5%
Computer Science 2 5%
Social Sciences 2 5%
Other 2 5%
Unknown 9 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2015.
All research outputs
#4,455,088
of 17,026,329 outputs
Outputs from Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd)
#364
of 1,042 outputs
Outputs of similar age
#73,979
of 289,999 outputs
Outputs of similar age from Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd)
#46
of 125 outputs
Altmetric has tracked 17,026,329 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,042 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,999 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.