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Circular RNA: new star, new hope in cancer

Overview of attention for article published in BMC Cancer, August 2018
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65 Mendeley
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Title
Circular RNA: new star, new hope in cancer
Published in
BMC Cancer, August 2018
DOI 10.1186/s12885-018-4689-7
Pubmed ID
Authors

Zikang Zhang, Qing Xie, Dongmei He, Yuan Ling, Yuchao Li, Jiangbin Li, Hua Zhang

Abstract

Circular RNAs are a new class of endogenous non-coding RNA that can function as crucial regulators of diverse cellular processes. The diverse types of circular RNAs with varying cytogenetics in cancer have also been reported. Circular RNAs can act as a microRNA sponge or through other mechanisms to regulate gene expression as either tumor inhibitors or accelerators, suggesting that circular RNAs can serve as newly developed biomarkers with clinic implications. Here, we summerized recent advances on circular RNAs in cancer and described a circular RNA network associated with tumorigenesis. The clinical implications of circular RNAs in cancer were also discussed in this paper. Growing evidence has revealed the crucial regulatory roles of circular RNAs in cancer and the elucidation of functional mechanisms involving circular RNAs would be helpful to construct a circRNA-miRNA-mRNA regulatory network. Moreover, circular RNAs can be easily detected due to their relative stability, widespread expression, and abundance in exosomes, blood and saliva; thus, circular RNAs have potential as new and ideal clinical biomarkers in cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 20%
Researcher 9 14%
Student > Master 7 11%
Student > Bachelor 5 8%
Student > Postgraduate 3 5%
Other 6 9%
Unknown 22 34%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 26%
Agricultural and Biological Sciences 7 11%
Medicine and Dentistry 6 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Immunology and Microbiology 3 5%
Other 5 8%
Unknown 24 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2018.
All research outputs
#15,018,183
of 23,102,082 outputs
Outputs from BMC Cancer
#3,716
of 8,386 outputs
Outputs of similar age
#199,794
of 333,703 outputs
Outputs of similar age from BMC Cancer
#73
of 145 outputs
Altmetric has tracked 23,102,082 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,386 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,703 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 145 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.