@mrtnj I liked this approach: https://t.co/RHRdCE9FTs
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@EduEyras @maralbasoler "Despite the large body of evidence describing its functional relevance" <- Debatable as to whether there is enough empirical evidence of functionally relevant alternative splicing https://t.co/h05RRDbccg
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Conclusion 2: remember to submit experimental results to Ensembl in order to help expand and re-use our knowledge on the functional role of isoforms. Communaction between wet and dry-lab scientists is crucial! https://t.co/NF6y0gwuyv
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In my view, the most concerning finding of the study is the discrepancy between DBs and the literature. Shocking how 1/3 of genes with FDSIs had isoforms not registered in Ensembl (20% in the case of UniProt). https://t.co/NF6y0gwuyv