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X Demographics
Mendeley readers
Attention Score in Context
Title |
Cancer's sweet tooth for serine
|
---|---|
Published in |
Breast Cancer Research, November 2011
|
DOI | 10.1186/bcr2932 |
Pubmed ID | |
Authors |
Ji Luo |
Abstract |
Exemplified by the cancer cell's preference for glycolysis (the Warburg effect), altered metabolism has taken centerstage as an emerging hallmark of cancer. Charting the landscape of cancer metabolic addictions should reveal new avenues for therapeutic attack. Two recent studies found subsets of human melanoma and breast cancers to have high levels of phosphoglycerate dehydrogenase (PHGDH), a key enzyme for serine biosynthesis, and these cancer cells are dependent on PHGDH for their growth and survival. Tumors may thus harbor distinct metabolic alterations to support their malignancy, and targeting enzymes such as PHGDH might prove a viable therapeutic strategy in this scenario. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 2% |
Unknown | 59 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 28% |
Researcher | 10 | 17% |
Student > Bachelor | 6 | 10% |
Student > Master | 5 | 8% |
Student > Postgraduate | 4 | 7% |
Other | 13 | 22% |
Unknown | 5 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 35% |
Biochemistry, Genetics and Molecular Biology | 13 | 22% |
Medicine and Dentistry | 8 | 13% |
Chemistry | 4 | 7% |
Business, Management and Accounting | 2 | 3% |
Other | 6 | 10% |
Unknown | 6 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2017.
All research outputs
#5,846,113
of 22,659,164 outputs
Outputs from Breast Cancer Research
#702
of 1,886 outputs
Outputs of similar age
#51,593
of 240,319 outputs
Outputs of similar age from Breast Cancer Research
#10
of 54 outputs
Altmetric has tracked 22,659,164 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,886 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,319 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.